Publications by authors named "Monika Mellar"
Article Synopsis
- PCDH19-related epilepsy primarily affects girls, starting around 15 months, often triggered by fever and marked by clustering of seizures, alongside symptoms like autism and intellectual disability.
- A study reviewing nine children with genetically confirmed PCDH19 epilepsy in Hungary indicated a lower prevalence in their population compared to international figures, with several patients showing brain anomalies and a significant occurrence of status epilepticus.
- Effective treatment with combined antiseizure medications was successful in seven out of nine children, highlighting the importance of genetic testing for early-onset seizures in females to improve diagnosis and treatment.
In our review we discuss the group of approved antiepileptic drugs for children in Hungary. We cite the results of the review conducted by the International League Against Epilepsy on antiepileptic drug efficacy and effectiveness as initial monotherapy for newly diagnosed epileptic seizures and syndromes in pediatric age group. 25% of pediatric epilepsy is therapy resistant, so we further need new drugs, which must be investigated according to the rules of the European Medicine Agency.
View Article and Find Full Text PDFVisual and neurologic deterioration in otogenic lateral sinus thrombosis: 15 year experience.
Int J Pediatr Otorhinolaryngol
August 2014
Objectives: Otogenic lateral sinus thrombosis is a rare complication of acute otitis media whose clinical presentation has changed with the early use of antibiotics. The aim of this study was to analyze the changing clinical signs, vaccination status, therapeutic management and outcome of these patients.
Methods: Retrospective chart review of 10 children treated with otogenic lateral sinus thrombosis in a tertiary level teaching hospital in Budapest, Hungary, from January 1998 till August 2013.