Antibacterial efficacy interference of the photocatalytic TiO nanoparticle and the lytic bacteriophage vb_EcoS_bov25_1D on the Enterohaemorragic strain Sakai.

Post-antibiotic era requires the use of alternative pesticides against bacterial infections. One potential application field is agriculture, where pesticides are routinely applied in combinations. In this study we tested the interference of antibacterial effects of two alternative antimicrobials with basically different mode of actions if applied together by using the Enterohemorrhagic strain Sakai as a modelorganism, one strain of a pathotype that is frequently associated with meat and plant derived infections.

[Antibacterial effect of local anaesthetics].

Összefoglaló. Gyógyszereink egy részének jelentős, az eredeti alkalmazástól eltérő hatása is van. Ezek felismerése fontos, hogy elkerüljük a nem várt mellékhatásokat, vagy kihasználjuk ezeket a kedvező adottságokat.

Amiodarone that has antibacterial effect against human pathogens may represent a novel catheter lock.

Infection is one of the most feared hospital-acquired complications. Infusion therapy is frequently administered through a central line. Infusions facilitating bacterial growth may be a source of central line-associated bloodstream infections.

Characterization of Asymptomatic Bacteriuria Isolates in Search of Alternative Strains for Efficient Bacterial Interference against Uropathogens.

Asymptomatic bacterial colonization of the urinary bladder (asymptomatic bacteriuria, ABU) can prevent bladder colonization by uropathogens and thus symptomatic urinary tract infection (UTI). Deliberate bladder colonization with ABU isolate 83972 has been shown to outcompete uropathogens and prevent symptomatic UTI by bacterial interference. Many ABU isolates evolved from uropathogenic ancestors and, although attenuated, may still be able to express virulence-associated factors.

Histological and antimicrobial study of Ononis arvensis L.

In this study field restharrow (Ononis arvensis) was investigated for histological and antimicrobial features. The aerial part and the root were embedded in synthetic resin and investigated following sectioning by a rotation microtome. The antimicrobial activity and minimum inhibitory concentration of the solvent fractions of the aerial part were studied against four bacterial strains and one fungus.

Atropine and glycopyrrolate do not support bacterial growth-safety and economic considerations.

Study Objective: Evaluation of bacterial growth in atropine and glycopyrrolate.

Design: Laboratory investigation.

Subjects And Measurements: Standard microbiological methods were used to evaluate the impact of atropine and glycopyrrolate on the growth of Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli.

A modified bioautographic method for antibacterial component screening against anaerobic and microaerophilic bacteria.

Direct bioautography is a useful method to identify antimicrobial compounds with potential therapeutic importance. Because of technical limitations till now, it has been applied only for aerobic bacteria. In this work we present the modification of the original method by which antimicrobial screening of bacteria requiring modified atmosphere became feasible by direct bioautography.

Re-evaluation of in vitro activity of primycin against prevalent multiresistant bacteria.

With the increasing emergence of antibiotic resistances old antibiotics became a valuable source to find agents suitable to address this problem. More than 20 years after the last report, our purpose was to re-evaluate the in vitro antibacterial activity of the topical agent primycin against current important bacterial pathogens. Minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) of primycin were tested in comparison with agents widely applied topically, and with those of mupirocin and vancomycin, the topical and the non-topical gold-standard anti-MRSA agents.

Interference in quorum sensing signal transmission amongst microbial species.

Antibiotics are usually studied on pure cultures of a single bacterial strain, whereas multi-species communities that inhabit human niches and the biosphere are generally ignored. The modification of quorum sensing (QS) is investigated in a system involving a co-existing signal producer and sensor bacterial cells. A pure culture of merely one bacterial species is quite rare in any niche.

A comparison of the antimicrobial property of lidocaine/prilocaine cream (EMLA) and an alcohol-based disinfectant on intact human skin flora.

Background: The application of EMLA cream is indicated for topical anesthesia of the skin in connection with IV cannulation. Recently, we described that EMLA cream has an antibacterial effect in vitro.

Methods: The impact of the local anesthetic lidocaine/prilocaine cream (EMLA) on intact human skin flora was compared to that of an alcohol-based skin disinfectant (Skinsept Pur).

Bacterial growth in ropivacaine hydrochloride.

Drugs affecting bacterial growth may influence the occurrence of postoperative infections. Ropivacaine 10 mg/mL killed Staphylococcus aureus and Escherichia coli; ropivacaine 2 mg/mL supported the growth of E. coli.