Performance of a deep learning enhancement method applied to PET images acquired with a reduced acquisition time.

Background: This study aims to evaluate the performance of a deep learning enhancement method in PET images reconstructed with a shorter acquisition time, and different reconstruction algorithms. The impact of the enhancement on clinical decisions was also assessed.

Material And Methods: Thirty-seven subjects underwent clinical whole-body [18F]FDG PET/CT exams with an acquisition time of 1.

Modifying impact of gene haplotypes on medullary thyroid carcinoma clinical course.

The clinical course of medullary thyroid carcinoma (MTC) associated with the MEN2A syndrome as well as of sporadic MTC shows considerable heterogeneity. The disease picture varies not only between the same proto-oncogene mutation carriers but also among sporadic MTC patients with no germinal mutations, which suggests the involvement of additional modulators of the disease. However, genetic factors responsible for this heterogeneity of the MTC clinical course still remain unknown.

Pituitary Microsomal Autoantibodies in Patients with Childhood-Onset Combined Pituitary Hormone Deficiency: an Antigen Identification Attempt.

The role of autoimmunization in the pathogenesis of pituitary disorders is poorly understood. The presence of pituitary autoantibodies (APA) has been detected in various pituitary disorders. Their role, however, remains elusive.

Diagnosis, treatment, and prognosis in patients with liver metastases from follicular thyroid carcinoma (FTC).

Follicular thyroid carcinoma (FTC) is the second most common type of thyroid cancer (TC) and accounts for approximately 10% of all TC cases. Liver metastases are a rare presentation in 0.5-1% of follicular thyroid cancers, usually occurring in the setting of widely disseminated FTC disease, and their presence is associated with poor prognosis.

The c.470 T > C CHEK2 missense variant increases the risk of differentiated thyroid carcinoma in the Great Poland population.

Background: Differentiated thyroid carcinoma (DTC) originates from thyroid follicular epithelial cells and belongs to a group of slowly progressing tumors with a relatively good prognosis. However, recurrences and metastases are a serious problem in advanced stages. Furthermore, progression from a well differentiated thyroid carcinoma to an aggressive anaplastic one is possible.

Emotional functions in transsexuals after the first step in physical transformation.

Transsexuals have to face multiple medical, social and bureaucratic problems. These problems are not only encountered before the transformation, but also during and after medical procedures. In the search for improvement of transsexual individuals' quality of life during therapy, it seems desirable to supplement hormonal treatments with psychological explorations.

gene polymorphic variants in patients with differentiated thyroid carcinoma.

Alterations in the gene affect the cell cycle and are frequently observed in a variety of cancers. While the most frequent mutations that occur in thyroid tumor tissue have been characterized, the genetic factors that predispose individuals to differentiated thyroid cancer (DTC) remain to be elucidated. The present study examined whether the c.

[Depression in Parkinson disease: own experience].

The aim of the study was to evaluate the frequency of depression in patients with Parkinson's disease. The authors recruited 85 patients with idiopathic Parkinson's disease, 42 males and 43 females aged 34-82 years (mean age 68.7).

[Significance of visual evoked potentials (VEP) in the diagnosis of Parkinson disease].

The aim of the study was to check whether VEP in Parkinson disease are pathological and if there is a relationship between VEP studies and severity, duration of the disease. The authors recruited 54 patient with idiopathic Parkinson disease with significant differences in laterality of bradykinesia, rigidity and tremor. The examined group consisted of 25 males and 29 females, aged from 34 to 82 years; mean age 70.