Publications by authors named "Monika Fischler"
Article Synopsis
- Researchers developed a new type of gold nanoparticle with azide functional groups.
- They used a method called click chemistry to couple these nanoparticles to a DNA duplex that has alkyne modifications.
- This process created a chain-like assembly of nanoparticles arranged along the DNA template.
Gold nanoparticles are widely used in biomedical imaging and diagnostic tests. Based on their established use in the laboratory and the chemical stability of Au(0), gold nanoparticles were expected to be safe. The recent literature, however, contains conflicting data regarding the cytotoxicity of gold nanoparticles.
View Article and Find Full Text PDFUniform bimetallic nanowires, tunable in size, have been grown on artificial DNA templates via a two-step metallization process. Alkyne-modified cytosines were incorporated into 900-base-pair polymerase-chain-reaction fragments. The alkyne modifications serve as addressable metal-binding sites after conversion to a sugar triazole derivative via click chemistry.
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