Publications by authors named "Monika Dzieciuch-Rojek"
Article Synopsis
- The CHART-1 study found that multiple injections of cardiopoetic cells in patients with chronic ischemic heart failure may diminish their therapeutic effects over time.
- Patients with low left ventricular ejection fraction (LVEF) underwent either cell transplantation or a sham procedure, and their heart function was assessed using echocardiography.
- Results indicated that a significant percentage of those receiving cardiopoetic cells experienced decreased heart contractility and increased wall motion score, suggesting that the injection technique may cause myocardial injury that outweighs potential benefits.
Cholesterol plays a crucial role in modulating the physicochemical properties of biomembranes, both increasing mechanical strength and decreasing permeability. Cholesterol is also a common component of vesicle-based delivery systems, including liposome-based drug delivery systems (LDSs). However, its effect on the partitioning of drug molecules to lipid membranes is very poorly recognized.
View Article and Find Full Text PDFItraconazole (ITZ) is an antifungal agent used clinically to treat mycotic infections. However, its therapeutic effects are limited by low solubility in aqueous media. Liposome-based delivery systems (LDS) have been proposed as a delivery mechanism for ITZ to alleviate this problem.
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