approach for identification of natural compounds as potential COVID 19 main protease (M) inhibitors.

Unlabelled: With the recent pandemic outbreak and subsequent worldwide spread of COVID-19 from Wuhan city of China, millions of infections and lakhs of deaths have resulted. No registered therapies have been developed to treat infection with COVID-19. The present study was conducted to evaluate the efficacy of herbal drugs as drug target molecules against COVID-19 by molecular docking.

Effect of temperature and pressure on antimycobacterial activity of extract by supercritical fluid extraction method.

Background: Supercritical fluid extraction (SFE) is an advanced technique using COas a solvent and plant-based drug exploration is a topic of growing interest. Curcuma caesia is a medicinal herb with many medicinal potential. Hence, in the present study, the effect of temperature (40°C-60°C) and pressure (10-20 MPa) on extraction yield and antimycobacterium potential of C.

Comparison of extracts for bioactive metabolite composition, antioxidant and antimicrobial potential.

The objective of this study was to compare the antioxidant and antibacterial activity of rhizome extracts and to characterise its bioactive metabolites by Fourier Transform-Infrared (FTIR) spectroscopy and Gas Chromatography-Mass Spectroscopy (GC-MS). Extracts were prepared using methanol, acetone and ethyl acetate by cold percolation methods. Compared to other extracts, methanol extract discovered to have the greatest antioxidant capacity.