Publications by authors named "Monika Bals-Pratsch"

Article Synopsis
  • A retrospective study examined the effects of glucose and insulin metabolism disorders on fertility in women who conceived spontaneously before planned assisted reproduction (ART), focusing on their pregnancy outcomes.
  • Out of 589 pregnancies analyzed, 129 women conceived spontaneously, with a live birth rate of 66.7% and a miscarriage rate noted in 32 women; 76% were treated with metformin for issues like polycystic ovary syndrome and gestational diabetes risk.
  • The study found that 55.8% of participants developed gestational diabetes (GDM), with a notable difference in insulin requirements for those on metformin versus those who weren't, and a higher prevalence of polycystic ovary syndrome in women who achieved live births
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Objective: There is a paucity of knowledge about long-term outcome issues in the bladder-exstrophy-epispadias complex (BEEC). Adult male BEEC patients were investigated in respect of bladder and renal function, fertility, genital function and psychosocial facts.

Patients And Methods: In a cross-sectional study, 17 adult male BEEC patients (mean age 23.

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Objectives: Genital and reproductive function have a strong effect on the quality of life of adolescent and adult male patients with the exstrophy-epispadias complex (EEC). According to the limited available data, early exstrophy reconstruction, as well as recurrent infectious or operative trauma, have been responsible for the low fertility rates.

Methods: We evaluated 21 adult male patients with EEC.

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Objective: To evaluate the risk of testicular damage from testicular biopsies that are carried out for testicular sperm extraction (TESE) in infertile men.

Design: Prospective controlled clinical study.

Setting: Academic hospital.

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Steroid 5alpha-reductase deficiency is a rare autosomal recessive disorder caused by mutations in the SRD5A2-gene, resulting in diminished dihydrotestosterone (DHT) formation and, hence, in a severe virilization deficit of the external genitalia in patients with 46,XY karyotype. The phenotype of affected individuals is variable and has been reported to range from completely female over genital ambiguity to normal male, depending on the type of mutation and its effect on enzyme activity. Here we report an adolescent 46,XY patient with predominantly female appearance, who had been gonadectomized in early infancy.

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Synopsis of recent research by authors named "Monika Bals-Pratsch"

  • - Monika Bals-Pratsch's research primarily focuses on reproductive health, particularly the impact of various medical conditions, such as gestational diabetes and metabolic disorders, on fertility and pregnancy outcomes in women planning to conceive.
  • - Her studies highlight the importance of optimizing glucose and insulin metabolism prior to conception, showcasing a significant rate of spontaneous conception among women undergoing preconception optimization efforts prior to assisted reproduction.
  • - Additionally, Bals-Pratsch has investigated long-term outcomes for male patients with congenital conditions (e.g., bladder-exstrophy-epispadias complex), assessing areas such as psychosocial status, continence, and reproductive function to improve understanding of life quality for affected individuals.