Publications by authors named "Monicke O Lima"
Research demonstrates the important role of genetic factors in attention-deficit/hyperactivity disorder (ADHD). DNA sequencing of families provides a powerful approach for identifying de novo (spontaneous) variants, leading to the discovery of hundreds of clinically informative risk genes for other childhood neurodevelopmental disorders. This approach has yet to be extensively leveraged in ADHD.
View Article and Find Full Text PDFGenetic and non-genetic factors contribute to obsessive-compulsive disorder (OCD), with strong evidence of familial clustering. Genomic studies in psychiatry have used the concepts of families that are "simplex" (one affected) versus "multiplex" (multiple affected). Our study compares demographic and clinical data from OCD probands in simplex and multiplex families to uncover potential differences.
View Article and Find Full Text PDFLatin American Trans-ancestry INitiative for OCD genomics (LATINO): Study protocol.
Am J Med Genet B Neuropsychiatr Genet
June 2024
Article Synopsis
- OCD is a mental health disorder that affects around 2% of the world but not much is known about its causes.
- Most genetic studies on OCD so far have mainly focused on people of European ancestry, which could lead to unfair treatment options for those from other backgrounds.
- The LATINO project is collecting DNA and health information from 5,000 people with OCD from Latin America to improve understanding of the disorder and develop better treatments for everyone.
Objective: Animal hoarding is a special manifestation of Hoarding Disorder, characterized by the accumulation of animals and failure to provide them with minimal care. The main objective of this systematic review is to evaluate the characteristics of animal hoarding with a focus on the profile of affected individuals and accumulation behavior features.
Methods: A systematic search of the literature using the electronic databases MEDLINE, SCOPUS and LILACS was conducted until October 2022.
Article Synopsis
- Obsessive-compulsive disorder (OCD) affects about 2% of people around the world, but we don’t know exactly what causes it.
- Most research so far has focused mainly on people of European descent, which can leave out important information for people from other backgrounds.
- The LATINO initiative aims to include 5,000 people with OCD from Latin America and other countries, helping to gather more diverse data to improve our understanding and treatment of OCD globally.