Publications by authors named "Monica Toribio"
Article Synopsis
- The diagnosis of endometriosis often occurs late due to reliance on invasive procedures like laparoscopy; researchers are exploring microRNAs as potential early biomarkers.
- A study involving 159 women found that serum levels of miR-30c-5p were significantly higher in those with endometriosis compared to healthy individuals, suggesting its effectiveness in diagnosis.
- The results indicate miR-30c-5p could serve as a minimally invasive biomarker for endometriosis, showing associations with pathways linked to cancer and neuronal processes.
Article Synopsis
- Women experiencing ovarian failure (OF) often show short telomeres and low telomerase activity, suggesting a link between telomere health and fertility issues; using sexual steroids to reactivate telomerase might improve IVF outcomes.
- A double-blind study with patients having diminished ovarian reserve showed that those treated with Danazol for 3 months had changes in telomere dynamics, although overall telomere length remained similar.
- Treatment with Danazol improved the maturity rate of oocytes in later ovarian stimulation cycles, indicating potential benefits for IVF success, but further studies are necessary to validate these findings.
Urine LH testing may be useful to confirm an LH surge after the GnRH agonist (GnRHa) trigger prior to oocyte retrieval in IVF. A prospective cohort study, including oocyte donors undergoing ovarian stimulation, treated with a GnRHa trigger for final oocyte maturation. Urine LH testing was performed at home, 12 h after the GnRHa trigger.
View Article and Find Full Text PDFObjective: To investigate the effect of letrozole-an oral aromatase inhibitor-on E(2), P, and LH levels when administered during the luteal phase after oocyte retrieval in IVF/intracytoplasmic sperm injection (ICSI) cycles.
Design: Prospective, randomized, placebo controlled trial.
Setting: University-affiliated private reproductive medicine center.