In-silico mechanistic analysis of adsorption of Iodinated Contrast Media agents on graphene surface.

The study aims at assessing the potential of graphene-based adsorbents to reduce environmental impacts of Iodinated Contrast Media Agents (ICMs). We analyze an extensive collection of ICMs. A modeling approach resting on molecular docking and Density Functional Theory simulations is employed to examine the adsorption process at the molecular level.

Probabilistic assessment of failure of infiltration structures under model and parametric uncertainty.

We focus on the quantification of the probability of failure (PF) of an infiltration structure, of the kind that is typically employed for the implementation of low impact development strategies in urban settings. Our approach embeds various sources of uncertainty. These include (a) the mathematical models rendering key hydrological traits of the system and the ensuing model parametrization as well as (b) design variables related to the drainage structure.

Formulation and probabilistic assessment of reversible biodegradation pathway of Diclofenac in groundwater.

We present a conceptual and mathematical framework leading to the development of a biodegradation model capable to interpret the observed reversibility of the Pharmaceutical Sodium Diclofenac along its biological degradation pathway in groundwater. Diclofenac occurrence in water bodies poses major concerns due to its persistent (and bioactive) nature and its detection in surface waters and aquifer systems. Despite some evidences of its biodegradability at given reducing conditions, Diclofenac attenuation is often interpreted with models which are too streamlined, thus potentially hampering appropriate quantification of its fate.

Natural springs protection and probabilistic risk assessment under uncertain conditions.

The study introduces a comprehensive framework for natural springs' protection and probabilistic risk assessment in the presence of uncertainty associated with the characterization of the groundwater system. The methodology is applied to a regional-scale hydrogeological setting, located in Northern Italy and characterized by the presence of high-quality natural springs forming a unique system whose preservation is of critical importance for the region. Diverse risk pathways are presented to constitute a fault tree model enabling identification of all basic events, each associated with uncertainty and contributing to an undesired system failure.

Pore-scale velocities in three-dimensional porous materials with trapped immiscible fluid.

We study and document the influence of wetting and nonwetting trapped immiscible fluid on the probability distribution of pore-scale velocities of the flowing fluid phase. We focus on drainage and imbibition processes within a three-dimensional microcomputed tomographic image of a real rock sample. The probability distribution of velocity magnitude displays a heavier tail for trapped nonwetting than wetting fluid.

Solute concentration at a well in non-Gaussian aquifers under constant and time-varying pumping schedule.

Our study is keyed to the analysis of the interplay between engineering factors (i.e., transient pumping rates versus less realistic but commonly analyzed uniform extraction rates) and the heterogeneous structure of the aquifer (as expressed by the probability distribution characterizing transmissivity) on contaminant transport.

Space-time mesh adaptation for solute transport in randomly heterogeneous porous media.

We assess the impact of an anisotropic space and time grid adaptation technique on our ability to solve numerically solute transport in heterogeneous porous media. Heterogeneity is characterized in terms of the spatial distribution of hydraulic conductivity, whose natural logarithm, Y, is treated as a second-order stationary random process. We consider nonreactive transport of dissolved chemicals to be governed by an Advection Dispersion Equation at the continuum scale.

Spurious elevation of serum potassium concentration measured in samples with thrombocytosis.

Background: Several factors that can lead to falsely elevated values of serum. Thrombocytosis is one of these factors, since breakage or activation of platelets during blood coagulation in vitro may lead to spurious release of potassium. The purpose of the study was to evaluate to which extent the platelet count may impact on potassium in both serum and plasma.

Relative importance of geostatistical and transport models in describing heavily tailed breakthrough curves at the Lauswiesen site.

We analyze the relative importance of the selection of (1) the geostatistical model depicting the structural heterogeneity of an aquifer, and (2) the basic processes to be included in the conceptual model, to describe the main aspects of solute transport at an experimental site. We focus on the results of a forced-gradient tracer test performed at the "Lauswiesen" experimental site, near Tübingen, Germany. In the experiment, NaBr is injected into a well located 52 m from a pumping well.