The role of the intestinal ultrasound in Crohn's disease diagnosis and monitoring.

Crohn's disease is characterized by persistent or recurrent chronic inflammation that may affect any segment of the gastrointestinal tract. It has an oscillating evolution, with periods of activity alternating with periods of remission. Crohn's disease has a significant impact on the economic status due to its increasing prevalence, often affecting young people.

Climate Change and Social Campaigns.

The impact of climate change on humanity and nature is increasingly evident. The atmosphere and oceans have warmed, leading to rising sea levels, a sharp drop in Arctic sea ice, floods, heatwaves, and fires. Calls to action are getting stronger.

Nonalcoholic fatty liver disease: epidemiology, pathogenesis and therapeutic implications.

The increase of the prevalence of nonalcoholic fatty liver disease in the context of the explosive epidemy of obesity worldwide over the last decades and the emergence of new effective therapies for viral hepatitis has brought this entity to the forefront of hepatologist concerns. Today is a certainty that fatty liver can complicate with cirrhosis and hepatocellular carcinoma; moreover, nonalcoholic fatty liver disease is the main cause of cryptogenic cirrhosis and the second cause of liver transplantation. This review revises the epidemiology of the disease, brings forward some progress in pathogenesis and outlines the directions to be followed in nonalcoholic fatty liver disease prevention and therapy.

Non-biopsy methods to determine hepatic fibrosis.

The prognosis and clinical management of chronic liver diseases are highly dependent on the extent of liver fibrosis. Bigger the fibrosis, worse the prognosis; and bigger the risk of progression to cirrhosis. In current practice, liver biopsy is most frequently performed to assess the grade of inflammation and stage of fibrosis thereby providing prognostic information on which to base treatment decisions upon.

The functional sphincter of Oddi disorder.

The sphincter of Oddi disorder (SOD) has been a controversial subject for many years, about which a lot has been written. However, new findings mainly using Endoscopic Retrograde Cholangiopancreatography (ERCP) and sphincter of Oddi manometry (SOM) demonstrate the fact of this diagnostic. SOD is just a part of a larger pathology, the tfunctional gastrointestinal disorders, which have been reconsidered as an important part of gastrointestinal diseases.