Localized Amyloidosis of the Sphenoid Sinus: A Case Report and a Descriptive Literature Review.

Amyloidosis is the process of extracellular deposition of protein fibrils and manifests pathologically as a systemic or localized process. Localized amyloidosis of the head and neck is uncommon, and involvement of the sphenoid sinus is exceedingly rare. We describe a case of localized amyloidosis isolated from the sphenoid sinus.

Biologic Agents for the Treatment of Chronic Rhinosinusitis With Nasal Polyps.

Background: Chronic rhinosinusitis with nasal polyposis is a complex inflammatory disorder, which is often recalcitrant to medical and surgical management. Recently, biologic agents have been studied as an adjunct treatment for this patient population.

Objective: The purpose of this study is to examine the role of biologic agents for chronic rhinosinusitis patients by reviewing literature and clinical trials.

Rare and Other Notable Complications in Endoscopic Sinus Surgery.

This article focuses on the rare and obscure complications of endoscopic sinus surgery. The majority of surgeons will not encounter these complications in their practice, but should be aware of their possibility. With knowledge of these rare complications, the surgeon can understand the possible avoidance as well as urgent management of these problems.

Role of immunotherapy in allergic fungal rhinosinusitis.

Purpose Of Review: Our understanding of the pathogenesis and treatment of allergic fungal rhinosinusitis (AFRS) continues to evolve. This article serves to update the reader on the diagnosis and management of AFRS and pays particular attention to the recent literature regarding efficacy and safety of immunotherapy in this patient population.

Recent Findings: The mainstay of treatment of AFRS remains a thorough surgery; however, adjunctive medical management is also critical to achieve optimal outcomes.

Asthma: symptoms and presentation.

The goal of this article is to inform readers of the common and uncommon signs and symptoms of asthma. After completion of this article, readers should have a firm understanding of the symptoms and presentation leading to a diagnosis of asthma.

Diagnosis of nasal airway obstruction.

Nasal airway obstruction is the source of significant patient discomfort and financial burden; hence, otolaryngologists encounter this symptom on an almost daily basis. This article provides a thorough yet concise summary of common and more specialized techniques that are instrumental in diagnosing nasal obstruction. The article begins with a brief overview of significant nasal anatomy and physiology.

Poor radiotherapy compliance predicts persistent regional disease in advanced head/neck cancer.

Objective: To determine if poor compliance to chemoradiation results in an increased rate of persistent neck disease.

Study Design: Retrospective, cohort study in an urban, tertiary-care medical center.

Methods: The study included patients with N+ stage III/IV squamous cell carcinoma of the upper aerodigestive tract treated with curative-intent chemoradiation, who underwent subsequent planned neck dissection.