Publications by authors named "Monica K Neuman"
Article Synopsis
- - This study looked at whether patients with stage IC grade 1 endometrioid ovarian carcinoma benefit from post-operative chemotherapy, using data from the National Cancer Institute's SEER program, involving 1207 patients treated between 2007 and 2020.
- - The findings showed that for patients with grade 1 tumors, there was no significant difference in 5-year survival rates (over 90%) whether or not they received chemotherapy, but those who didn't have nodal evaluation had significantly lower survival rates compared to those who did.
- - The implications suggest that while chemotherapy may not be necessary for grade 1 tumors with nodal evaluation, it becomes crucial for patients without such evaluations, indicating a need for tailored treatment approaches based on
Article Synopsis
- The 3-2-1 approach is a surgical method proposed to manage cesarean hysterectomy for placenta accreta spectrum (PAS) with the goal of reducing complications and improving outcomes.
- It involves three main steps: first, identifying three anatomical landmarks to create a safe surgical site; second, utilizing a two-hand technique to gently elevate the uterus and placenta; and third, considering a supracervical hysterectomy to better handle the situation.
- The overall aim is to enhance safety and efficiency during surgery by following this structured approach.
Importance: Isolated tumor cells (ITCs) are the histopathological finding of small clusters of cancer cells no greater than 0.2 mm in diameter in the regional lymph nodes. For endometrial cancer, the prognostic significance of ITCs is uncertain.
View Article and Find Full Text PDFObjective: To assess survival outcomes of stage IA3 endometrial cancer and the association of adjuvant therapy and survival.
Methods: The National Cancer Database was retrospectively queried to examine 594 and 1455 patients with stage IA3 and IIIA1 endometrial cancer, respectively, from 2010-2015. Overall survival (OS) was examined based on adjuvant therapy: multimodal combination chemotherapy and external beam radiotherapy, chemotherapy alone, external beam radiotherapy alone, and none.
Objectives: A lack of diversity amongst participants in cancer clinical trials has raised scrutiny over the past decade. Patients with limited English proficiency (LEP) are further excluded. One modifiable reason for low LEP participation is a lack of non-English consent forms.
View Article and Find Full Text PDFMany women see an obstetrician/gynecologist (OB/GYN) annually and receive their primary care from an OB/GYN. Understanding OB/GYNs' human papillomavirus (HPV) vaccination practices, including knowledge of and barriers to vaccination, is essential to design effective interventions to increase vaccination. This study evaluated OB/GYN knowledge, attitudes, and beliefs regarding vaccinating both younger (18-26 years) and mid-adult (27-45 years) women.
View Article and Find Full Text PDFArticle Synopsis
- * While NF-κB is important for immune function and fighting tumors, targeting it for therapy presents challenges because inhibiting this pathway could also affect normal tissues, complicating treatment.
- * There is ongoing research to find effective ways to inhibit NF-κB in tumors specifically, aiming to curb cancer growth while preserving the immune response against tumors.
Importance: Cartilaginous craniofacial defects range in size and autologous cartilaginous tissue is preferred for repair of these defects. Therefore, it is important to have the ability to produce large size cartilaginous constructs for repair of cartilaginous abnormalities.
Objectives: To produce autologous human septal neocartilage constructs substantially larger in size than previously produced constructsTo demonstrate that volume expanded neocartilage constructs possess comparable histological and biochemical properties to standard size constructsTo show that volume expanded neocartilage constructs retain similar biomechanical properties to standard size constructs.
Objectives/hypothesis: To localize quantitatively the major biochemical constituents of native adult human septal cartilage across whole septa.
Study Design: Prospective, basic science.
Methods: The nasal septa from seven cadavers were partitioned into 24 separate regions: six from caudal to cephalic and four from dorsal to ventral.
Shape fidelity of native and engineered human nasal septal cartilage.
Otolaryngol Head Neck Surg
May 2013
Objective: To test engineered and native septal cartilage for resistance to deformation and remodeling under sustained bending loads and to determine the effect of bending loads on the biochemical properties of constructs.
Study Design: Prospective, basic science.
Setting: Laboratory.