Live birth of twins after IVF of oocytes that were cryopreserved almost 12 years before.

A 45-year-old woman received embryos from IVF by intracytoplasmic sperm injection (ICSI) with her own oocytes that were cryopreserved (slow freezing in a low-sodium medium) 11 years and 7 and a half months before, when she was 33 years old. From seven metaphase-II oocytes thawed, five survived, four were fertilized after ICSI and two cleaving embryos were transferred on day 3. A diamniotic dichorionic term pregnancy was achieved, ending with the delivery of two healthy girls.

Birth of two babies using oocytes that were cryopreserved in a choline-based freezing medium.

Background: Oocyte cryopreservation may have significant potential for assisted reproductive technology. However, to date, successful results have been limited. We report a preliminary series of IVF outcomes after fertilization of oocytes that were frozen in a low-sodium medium.

Birth of a healthy baby after transfer of embryos that were cryopreserved for 8.9 years.

Objective: To report successful pregnancy from embryos that had been cryopreserved for 8.9 years.

Design: Case report.