Publications by authors named "Monica I Meneses-Medina"
Article Synopsis
- The study assessed 5-year survival rates for colorectal cancer patients in Mexico who were treated under Seguro Popular, a public health insurance system.
- It involved 1418 patients diagnosed between 2013 and 2016, revealing an overall survival rate of 50% and noting that 78.1% were diagnosed at advanced stages (III and IV).
- Findings emphasized the importance of early screening, particularly as younger patients with metastatic disease had a poorer prognosis compared to older patients.
Purpose: Neoadjuvant chemotherapy (NAC) significantly improved the prognosis of patients with locally advanced gastric cancer (LAGC). Several biomarkers, including HER2 and MMR/MSI are crucial for treatment decisions in the advanced stage but, currently, no biomarkers can guide the choice of NAC in clinical practice. Our aim was to evaluate the role of MSI and HER2 status on clinical outcomes.
View Article and Find Full Text PDFPurpose Of Review: Cyclin-dependent kinases (CDKs) are key regulators that play an important role in cell division. Palbociclib, ribociclib and abemaciclib showed significant antitumor activity in several malignancies and, recently, also a myeloprotective effect for trilaciclib when added to chemotherapy. The purpose of this review is to highlight the current evidence for CDK4/6 inhibitors in neuroendocrine neoplasms (NENs).
View Article and Find Full Text PDFArticle Synopsis
- The study compares the effectiveness of two treatment regimens, FOLFIRINOX and GEM-NAB, for pancreatic ductal adenocarcinoma, aiming to identify which regimen is more effective in cytoreduction.
- A meta-analysis incorporated data from 40 studies involving 2883 patients, finding that while both regimens had similar overall response rates (ORR) of around 30%, FOLFIRINOX exhibited a higher disease control rate (DCR) of 85% compared to GEM-NAB's 80%.
- Although no significant superiority was found between the regimens in terms of RECIST-based cytoreduction, the study suggests further investigation into the better DCR
SARS-CoV-2 Infection Rate in Patients With Cancer and Health Care Workers in a Chemoradiotherapy Unit During the Pandemic: A Prospective Cohort in Mexico.
JCO Glob Oncol
September 2021
Purpose: Cancer treatment during the COVID-19 pandemic represents a challenge. Hospital visits to receive treatment and interaction with health care workers (HCW) represent potential contagious events. We aimed to determine SARS-CoV-2 infection rate among patients with cancer and HCW of a chemoradiotherapy unit localized in a center designated as a COVID-19 priority facility in Mexico City.
View Article and Find Full Text PDFPurpose: The current first - line treatment for non - seminomatous germ cell tumor (NSGCT) consists of four cycles of cisplatin, etoposide, and bleomycin (BEP), which results in 5 - year overall survival < 60% in patients with poor - risk features. Autologous hematopoietic stem cell transplantation (auto - HSCT) as a method for overcoming high toxicity after high dose chemotherapy (HDC) has been explored in different solid tumors, but has remained standard practice only for NSGCT. Our objective was to describe outcomes of patients with poor - risk NSGCT who underwent first - line autologous HSCT in a tertiary center in Mexico.
View Article and Find Full Text PDF