ThyroidEx: Development and Preliminary Validation of a Thyroid Surgery Expectations Measure.

Objective: To address the lack of validated patient-reported outcome (PRO) instruments that define and quantify patient expectations in thyroid cancer surgery, we developed and initially validated ThyroidEx, a novel disease-specific PRO instrument.

Study Design: Survey study.

Setting: Single-institution tertiary care cancer center.

Distant Metastases in Patients with Carcinoma of the Major Salivary Glands.

Background: This study aimed to show the incidence of distant metastases (DM) in salivary gland cancer as well as the types of histology most commonly associated with it and to identify factors predictive of DM.

Methods: The study identified 301 patients who underwent surgery for cancer of the major salivary glands at Memorial Sloan-Kettering Cancer center between 1985 and 2009. Clinical, tumor, and treatment characteristics were recorded.

Treatment of the neck in carcinoma of the parotid gland.

Purpose: To review our experience in the treatment of the neck in patients with carcinoma of the parotid gland.

Methods: A total of 263 patients were stratified into 3 groups: no neck dissection (NoND), elective neck dissection (END), and therapeutic neck dissection (TND). Clinicopathological characteristics of END and TND versus NoND were compared by Chi square test.

Postoperative nomograms predictive of survival after surgical management of malignant tumors of the major salivary glands.

Objectives: The objective of this study was to create a nomogram predictive of survival in salivary gland cancer.

Methods: Clinical, tumor, and treatment characteristics were collected for 301 patients who underwent surgery for salivary gland cancer between 1985 and 2009 at Memorial Sloan Kettering Cancer Centre. Factors predictive of overall survival (OS) and cancer-specific survival (CSS) were determined by univariate analysis.

False-positive FNA due to highly sensitive BRAF assay.

Objective: False-positive BRAF analysis on fine-needle aspiration (FNA) has rarely been reported in the literature but may become more common with the advent of assays that can detect the BRAF V600E mutation in only 2% of otherwise wild-type thyroid cells. We present the case of an indeterminate BRAF-positive FNA that showed no evidence of cancer on final surgical pathology.

Methods: Case report and literature review.

A predictive nomogram for recurrence of carcinoma of the major salivary glands.

Importance: This nomogram quantifies the risk of recurrence in patients with carcinoma of the major salivary glands. It may facilitate patient counseling on prognosis and may help guide management and posttreatment surveillance in these patients.

Objectives: To identify factors predictive of recurrence after primary surgical treatment of carcinoma of the major salivary glands and create a nomogram that could be used to predict the risk of recurrence in an individual patient.

Selective use of radioactive iodine in intermediate-risk papillary thyroid cancer.

OBJECTIVE To describe the outcomes with the selective use of radioactive iodine (RAI) in patients who are at intermediate risk of death from papillary thyroid cancer, focusing on 2 subgroups: patients older than 45 years with low-risk tumors and patients younger than 45 years with high-risk tumors. DESIGN Retrospective case review. SETTING Tertiary referral US cancer center.