Hilab System Device in an Oncological Hospital: A New Clinical Approach for Point of Care CBC Test, Supported by the Internet of Things and Machine Learning.

The complete blood count (CBC) is a highly requested test that is generally restricted to centralized laboratories, which are limited by high cost, being maintenance-demanding, and requiring costly equipment. The Hilab System (HS) is a small, handheld hematological platform that uses microscopy and chromatography techniques, combined with machine learning (ML) and artificial intelligence (AI), to perform a CBC test. This platform uses ML and AI techniques to add higher accuracy and reliability to the results besides allowing for faster reporting.

Hilab system, a new point-of-care hematology analyzer supported by the Internet of Things and Artificial Intelligence.

The complete blood count (CBC) is one of the most requested tests by physicians. CBC tests, most realized in conventional hematological analyzers, are restricted to centralized laboratories due to frequent maintenance, large devices, and expensive costs required. On the other hand, most handheld CBC devices commercially available show high prices and are not liable to calibration or control procedures, which results in poor quality compared to standard hematology instruments.

The phylogeny of the Casque-headed Treefrogs (Hylidae: Hylinae: Lophyohylini).

The South American and West Indian Casque-headed Treefrogs (Hylidae: Hylinae: Lophyohylini) include 85 species. These are notably diverse in morphology (e.g.

The Influence of Saliva pH on the Fracture Resistance of Three Complete Denture Base Acrylic Resins.

Methods: Ten prosthesis bases prepared with each brand of resin were subjected to neutral and low pH conditions (pH 7 and pH 4) by submerging them in artificial saliva for 30 days. After exposure, the fatigue resistance of the resins was tested using a Dental CS® Testing Machine. .

Talon cusp in the temporary dentition of a patient with Kabuki syndrome: Case report with a two-year follow-up.

The presence of dental abnormalities in the same individual may be related to syndromic cases and occur through associated systemic changes. Kabuki syndrome presents well-defined systemic changes, but its clinical characteristics related to the oral cavity have not been fully explained. This study aimed to report the dental changes in a child diagnosed with Kabuki syndrome.

Relationship between functional masticatory units and cognitive impairment in elderly persons.

Background: Studies on the elderly have reported that the risk of cognitive impairment is affected by chewing difficulty.

Objective: To determine whether there is a relationship between the number of pairs of antagonist teeth that come into contact when the mouth is closed (functional masticatory units [FMUs]) and the level of cognitive impairment.

Methods: We conducted a cross-sectional observational study with 502 institutionalised White individuals older than 65 years, living in the northwest of Spain and Portugal.

Novel Putative Long Non-Coding RNAs: Interspecies Conservation Analysis in Adaptive Response to Different Biomes.

Long non-coding RNAs (lncRNAs) are involved in multiple regulatory pathways and its versatile form of action has disclosed a new layer in gene regulation. LncRNAs have their expression levels modulated during plant development, and in response to stresses with tissue-specific functions. In this study, we analyzed lncRNA from leaf samples collected from the legume Desf.

Bauhinia forficata in the treatment of diabetes mellitus: a patent review.

Introduction: Diabetes Mellitus has been considered an epidemic by the World Health Organization, with a high risk of morbidity and mortality. The treatment of this pathology consists in glycemic control, which can be done by oral hypoglycemic agents, insulin therapy, dietary guidance, regular physical activity, and psychosocial support. In addition, other adjuvant treatments are employed, such as phytotherapic, and one of the most used plants is Bauhinia forficata.

Cost comparison of genioplasty: when indicated, wire osteosynthesis is more cost effective than plate and screw fixation.

Purpose: This retrospective study was conducted to determine the difference in the cost of genioplasty according to the osseous fixation technique used.

Patients And Methods: A retrospective study among orthognathic surgery patients treated over a 54-month period ending in June 30, 2011 was conducted. Immediately post surgery, panoramic and cephalometric radiographs of these patients were assessed to determine the presence of genioplasty procedure and the type of fixation used.

Effect of dexamethasone on prevention of postoperative nausea, vomiting and pain after caesarean section: a randomised, placebo-controlled, double-blind trial.

Context: Spinal morphine is a common form of postoperative analgesia after caesarean section, but it is associated with postoperative nausea and vomiting.

Objective: To evaluate the hypothesis that dexamethasone reduces nausea and vomiting in patients undergoing caesarean section under spinal anaesthesia with morphine.

Design: Interventional, randomised, double-blinded, placebo-controlled study to evaluate a preoperative single dose of dexamethasone.

DNA barcoding Bromeliaceae: achievements and pitfalls.

Background: DNA barcoding has been successfully established in animals as a tool for organismal identification and taxonomic clarification. Slower nucleotide substitution rates in plant genomes have made the selection of a DNA barcode for land plants a much more difficult task. The Plant Working Group of the Consortium for the Barcode of Life (CBOL) recommended the two-marker combination rbcL/matK as a pragmatic solution to a complex trade-off between universality, sequence quality, discrimination, and cost.

Clinical evaluation of the flotrac/Vigileo system for continuous cardiac output monitoring in patients undergoing regional anesthesia for elective cesarean section: a pilot study.

Background: Spinal anesthesia for cesarean delivery may cause severe maternal hypotension and a decrease in cardiac output. Compared to assessment of cardiac output via a pulmonary artery catheter, the FloTrac/Vigileo system may offer a less invasive technique. The aim of this study was to evaluate cardiac output and other hemodynamic measurements made using the FloTrac/Vigileo system in patients undergoing spinal anesthesia for elective cesarean section.

Epigenetic variation in mangrove plants occurring in contrasting natural environment.

Background: Epigenetic modifications, such as cytosine methylation, are inherited in plant species and may occur in response to biotic or abiotic stress, affecting gene expression without changing genome sequence. Laguncularia racemosa, a mangrove species, occurs in naturally contrasting habitats where it is subjected daily to salinity and nutrient variations leading to morphological differences. This work aims at unraveling how CpG-methylation variation is distributed among individuals from two nearby habitats, at a riverside (RS) or near a salt marsh (SM), with different environmental pressures and how this variation is correlated with the observed morphological variation.

An experimental paradigm for the prediction of Post-Operative Pain (PPOP).

Many women undergo cesarean delivery without problems, however some experience significant pain after cesarean section. Pain is associated with negative short-term and long-term effects on the mother. Prior to women undergoing surgery, can we predict who is at risk for developing significant postoperative pain and potentially prevent or minimize its negative consequences? These are the fundamental questions that a team from the University of Washington, Stanford University, the Catholic University in Brussels, Belgium, Santa Joana Women's Hospital in São Paulo, Brazil, and Rambam Medical Center in Israel is currently evaluating in an international research collaboration.

Effects of the addition of subarachnoid clonidine to the anesthetic solution of sufentanil and hyperbaric or hypobaric bupivacaine for labor analgesia.

Background And Objectives: The addition of subarachnoid clonidine (alpha-agonist) prolongs the analgesia produced by the combination of sufentanil and isobaric bupivacaine in combined labor analgesia(1). The objective of this study was to compare the quality of analgesia and the prevalence of side effects after the addition of subarachnoid clonidine to the anesthetic solution in labor analgesia.

Methods: After approval by the Ethics Commission, 22 pregnant women in labor were randomly assigned to the subarachnoid administration of either 2.

[Oxytocin in cesarean sections: what is the best way to use it?].

Background And Objectives: Oxytocin is the uterotonic used in obstetric anesthesia, and its prophylactic and therapeutic administration is justified because it reduces the incidence of post-partum hemorrhage. However, the ideal infusion regimen in elective cesarean sections has not been determined yet. The objective of this study was to review the main physiological and pharmacological characteristics of oxytocin and to discuss its rational use by anesthesiologists in view of its side effects.

[The effect of adding subarachnoid clonidine to hyperbaric bupivacaine and sufentanil during labor analgesia.].

Background And Objectives: Adding subarachnoid clonidine (an alpha -agonist) prolongs the analgesic effect of the combination of sufentanil and isobaric bupivacaine when combined during labor analgesia. The aim of this study was to compare the quality and duration of the analgesia as well as the incidence of side-effects after the addition of subarachnoid clonidine to hyperbaric bupivacaine and sufentanil in a combined spinal-epidural analgesia during labor.

Methods: Twenty-six patients, physical status ASA I in full-term pregnancy were studied.

[Preload during spinal anesthesia for cesarean section: comparison between crystalloid and colloid solutions.].

Background And Objectives: Maternal hypotension is the most common complication following spinal anesthesia for cesarean section. This study aimed at comparing the incidence of hypotension and the need for vasopressors in patients submitted to cesarean section under spinal anesthesia following preload with either crystalloid or colloid (modified fluid gelatin).

Methods: Participated in this prospective study 50 term pregnant patients, physical status ASA I, submitted to cesarean section under spinal anesthesia.

[Spinal sufentanil associated to hyperbaric bupivacaine: Is it possible to decrease opioid dose?].

Background And Objectives: The association of isobaric bupivacaine to lower spinal sufentanil dose provides satisfactory analgesia and lower incidence of side effects. This study aimed at evaluating quality of analgesia and incidence of side effects of decreased spinal sufentanil doses associated to hyperbaric bupivacaine for labor analgesia.

Methods: Participated in this study 69 healthy term pregnant patients in active labor.

Fluid preload in obstetric patients. How to do it?

Background And Objectives: In has been shown in non-obstetric patients, that a fast acute fluid preload immediately after spinal anesthesia was more effective than a slow preload before regional block to decrease the incidence and severity of arterial hypotension after spinal anesthesia. This study aimed at comparing the incidence of arterial hypotension and vasopressants consumption in parturients submitted to C-section under spinal anesthesia with different fluid preload regimens.

Methods: Sixty term pregnant women submitted to C-section under spinal anesthesia.

[Post-cesarean section analgesia with low spinal morphine doses and systemic nonsteroidal anti-inflammatory drug: diclofenac versus ketoprofen.].

Background And Objectives: The association of low spinal morphine doses and muscular diclofenac is effective to control postoperative pain after Cesarean section under spinal anesthesia. Ketoprofen, also an NSAID, may be advantageous over diclofenac because it may be intravenously administered. This study aimed at comparing the analgesic efficacy of diclofenac and ketoprofen in association to low spinal morphine doses in the immediate postoperative period of patients submitted to Cesarean section under spinal anesthesia.

[Intramuscular versus rectal diclofenac associated with low dose spinal morphine for post-cesarean analgesia.].

Background And Objectives: Diclofenac has been used in combination with spinal opioids to control postoperative pain; however, the best regimen of its administration is not known. This study evaluated the quality of postoperative analgesia of different regimens of diclofenac administration, in patients submitted to Cesarean section under spinal anesthesia with bupivacaine and morphine.

Methods: After the end of surgery, patients were randomly allocated into three groups that received diclofenac as follows: G50VR(n=62), 50 mg rectally; G50IM(n=62), 50 mg intramuscularly and G75IM (n=62), 75 mg intramuscularly.