Background: Nasal continuous positive airway pressure, nasal intermittent positive pressure ventilation, and non-invasive neurally adjusted ventilatory assist are modes of non-invasive respiratory support. The objective was to investigate if cardiorespiratory measures performed shortly after extubation are associated with extubation outcomes and predictors of extubation success.
Methods: Randomized crossover trial of infants with birth weight (BW) ≤ 1250 g undergoing their first extubation.
Objective: Investigate the cardiorespiratory effects of noninvasive neurally adjusted ventilatory assist (NIV-NAVA), nonsynchronized nasal intermittent positive pressure ventilation (NIPPV), and nasal continuous positive airway pressure (NCPAP) shortly after extubation.
Hypothesis: Types of noninvasive pressure support and the presence of synchronization may affect cardiorespiratory parameters.
Study Design: Randomized crossover trial.
Background: Extremely preterm infants are often exposed to endotracheal tube continuous positive airway pressure (ETT-CPAP) trials to assess extubation readiness. The effects of ETT-CPAP trial on their diaphragmatic activity (Edi) and breathing variability is unknown.
Methods: Prospective observational study enrolling infants with birth weight ≤1250 g undergoing their first extubation attempt.