Steam distillation, supercritical fluid extraction, and anti- activity of compounds from pink pepper ( Raddi).

Anti- activity of compounds from fruits of Raddi (pink pepper) were evaluated, using sustainable techniques such as steam distillation (SD) and supercritical fluid extraction (SFE). SD was optimised using a design of experiment and SFE was carried out using supercritical CO solvent (300 bar and 60 °C). Results of the anti- activity showed that the essential oil presented high activity (IC = 4.

Exploring visible light enhancement for sensing: an azo-dye decorated gold nanoantenna monitored with a smartphone app.

Optical sensors can be used to detect a variety of substances ranging from diagnostics on biological samples to the detection of hazardous substances. This type of sensor can be a valuable alternative to more complex analytical techniques, being fast and requiring little to no sample preparation at the expense of the reusability of the device. Here, we show the construction of a colorimetric nanoantenna sensor using gold nanoparticles (AuNPs) embedded in poly(vinyl alcohol) (PVA) and decorated with the methyl orange (MO) azo dye (AuNP@PVA@MO) that is potentially reusable.

Multivariate probing of antitumor metal-based complexes damage on living cells through Raman imaging.

Intracellular modifications caused by two metal-based antitumor compounds were assessed by confocal Raman imaging assisted by multivariate curve resolution method, a very powerful deconvolution tool that can be used to extract the characteristic spectral profile of the individual or "purest" components from an image dataset. The use of this Raman methodology has the advantage of being non-invasive and totally label-free. Four main different intracellular processes were observed under the Raman imaging and multivariate approach combination, and even, significant differences could be identified between the treatments with both metallodrugs.