Publications by authors named "Monia Trasolini"

Correct classification of irritability is extremely important to assess prognosis and treatment indications of juvenile mood disorders. We assessed factors associated with low versus high parent- and self-rated irritability using the affective reactivity index (ARI) in a sample of 289 adolescents diagnosed with a bipolar or a major depressive disorder. Bivariate analyses were followed by multilinear logistic regression model.

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Objective: To identify childhood psychopathological features that predict the onset of adolescent Bipolar (BD) versus Unipolar Major Depressive Disorder (UD) during adolescence.

Method: We analyzed clinical data from 495 juveniles diagnosed with DSM-5 UD ( = 359), and BD ( = 136), using bivariate analysis and multivariate logistic regression model.

Results: BD subjects exhibited earlier onset of any psychiatric feature compared to UD.

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Background: Gender differences have been reported in the severity and psychopathological features of major depressive disorders among adults but are poorly reported in adolescent samples.

Objective: This study aimed to examine gender differences in the psychopathology of mixed depression among adolescents.

Methods: We analyzed 341 outpatients with the current major depressive episode (MDE) retrospectively to identify patients with DSM-5 MDE with mixed features.

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Article Synopsis
  • Noonan syndrome (NS) is a genetic developmental disorder linked to mutations in the Ras-MAPK signaling pathway, resulting in variable clinical symptoms.
  • This study evaluates the psychopathological features, particularly depressive and hypo-manic symptoms, in 37 children and adolescents with NS, finding significant signs of attention deficit, irritability, emotional dysregulation, and anxiety.
  • The average cognitive levels of the subjects were found to be normal, emphasizing the importance for clinicians to monitor mood disorders in individuals with Noonan syndrome.
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