Towards Robust Causal Inference in Epidemiological Research: Employing Double Cross-fit TMLE in Right Heart Catheterization Data.

Within epidemiological research, estimating treatment effects from observational data presents notable challenges. Targeted Maximum Likelihood Estimation (TMLE) emerges as a robust method, addressing these challenges by accurately modeling treatment effects. This approach uniquely combines the precision of correctly specified models with the versatility of data-adaptive, flexible machine learning algorithms.

Environmental factors regulating the population dynamics and reproductive strategy of freshwater mussel in the Padma River, Bangladesh.

Freshwater mussel is an ecologically important species endemic to south-east Asia, which has been suffering from a dramatic decline in recent years. The present study investigated the population dynamics and reproductive strategy of in a changing climate of Bangladesh waters. Mussels were sampled monthly from January to December 2021 from the Padma River near the Rajshahi city of Bangladesh.

Association of Admission Glycemic Gap on Short-term Outcome of Neuro-critical Patients with Diabetes.

Both of neurological emergencies and hyperglycemia are independently associated risk factors of mortality in the ICU patients. In critically ills, hyperglycemia is secondary to already existing DM or stress-induced hyperglycemia (SIH). Admission glycemic gap (AGG) is considered as a reliable indicator of SIH.

Sex-Specific Association of Ambient Temperature With Urine Biomarkers in Southwest Coastal Bangladesh.

Introduction: Men are vulnerable to ambient heat-related kidney disease burden; however, limited evidence exists on how vulnerable women are when exposed to high ambient heat. We evaluated the sex-specific association between ambient temperature and urine electrolytes, and 24-hour urine total protein, and volume.

Methods: We pooled a longitudinal 5624 person-visits data of 1175 participants' concentration and 24-hour excretion of urine electrolytes and other biomarkers (24-hour urine total protein and volume) from southwest coastal Bangladesh (Khulna, Satkhira, and Mongla districts) during November 2016 to April 2017.

Green synthesis of zinc oxide nano particles using L. waste peel extracts and its antioxidant and antibacterial activities.

Synthesis of nanoparticles through the green approach using plant and vegetable extracts has gained popularity since they are thought to be efficient and cost-effective materials. This study is designed to synthesize zinc oxide nanoparticles (ZnO-NPs) from onion waste peel extract ( L.) via the green synthesis approach.

Fabrication and performance analysis of keratin based-graphene oxide nanocomposite to remove dye from tannery wastewater.

In recent years, nanomaterials and composites have become increasingly significant as adsorbents in the removal of dyes and phenolic contaminants from wastewater. This study presents the development and application of a keratin-based graphene oxide nanocomposite, distinguished by its enhanced biocompatibility, cost-effectiveness, and strong affinity for organic compounds, making it highly effective in reducing dyes within tannery effluent. The nanocomposite was prepared via solution casting method, with dispersibility, chemical bonding, and morphology analyzed by UV-Vis spectroscopy, FTIR, and SEM, respectively.

Association of Chest Pain with Rate Pressure Product and ST-segment Changes after Sub Arachnoid Block in Caesarean Section.

When healthy women undergo caesarean section (CS) under sub arachnoid anaesthesia, transient electrocardiographic changes, such as ST-segment depression and T-wave abnormalities, are observed. During an elective caesarean section under sub arachnoid anaesthesia, about one-third of healthy parturient experience chest pain and ECG changes suggestive of myocardial ischemia. To assess the ST-segment and Rate Pressure Product changes with chest pain in patients with elective caesarean section under subarachnoid block.

Evaluation of transfer factors of Ra, Th, and K radionuclides from soil to grass and mango in the northern region of Bangladesh.

Bangladesh is a rapidly developing country, which is vulnerable to various types of pollution due to the large-scale industrial and associated human activities that might potentially affect the locally harvested foodstuffs. Therefore, the transfer factor is an essential tool to assess the safety of foodstuffs due to the presence of natural radioactivity in environmental matrix and/or strata. This is a first study of its kind conducted in a well-known region for mango farming in Bangladesh, measuring the uptake of naturally occurring radioactive materials (NORMs) by grass and mango from soil to assess the ingestion doses to humans.

Spatiotemporal drought analysis in Bangladesh using the standardized precipitation index (SPI) and standardized precipitation evapotranspiration index (SPEI).

Countries depending on small-scale agriculture, such as Bangladesh, are susceptible to climate change and variability. Changes in the frequency and intensity of drought are a crucial aspect of this issue and the focus of this research. The goal of this work is to use SPI (standardized precipitation index) and SPEI (standardized precipitation evapotranspiration index) to investigate the differences in drought characteristics across different physiognomy types in Bangladesh and to highlight how drought characteristics change over time and spatial scales when considering different geomorphologies.

Pore creation nanoarchitectonics from non-porous metal-organic framework to porous carbon for adsorptive elimination of sulfanilamide and chloroxylenol from aqueous solution.

Three isomeric metal-organic frameworks (MOFs) such as MAF-5, - 6, and - 32 (with the same composition of [Zn(2-ethylimidazole)]) were carbonized and, for the first time, activated further with KOH to prepare highly porous MOF-derived carbons (MDCs). Importantly, MDC-32 derived from non-porous MAF-32 had the highest porosity among the three MDCs although it has the lowest porosity when no KOH activation was done. Adsorption of sulfanilamide and chloroxylenol from water was investigated with the MDCs.

Functionalized metal-organic framework-derived carbon: Effective adsorbent to eliminate methylene blue, a small cationic dye from water.

Elimination of organic dyes from wastewater is very important for our safe environment and sound health. In this work, adsorptive removal of cationic dyes, especially small ones, was investigated with carbonaceous materials to develop a competitive adsorption technology. To improve the performance of metal-organic framework (MOF)-derived carbons (MDCs) in dye adsorption, an MDC, derived from a MOF (MAF-6), was oxidatively functionalized with ammonium persulfate solutions (APSs).

Comparative performance analysis of 2D and 3D gamma metrics for patient specific QA in VMAT using Octavius 4D with 2D-Array 1500.

Introduction: Gamma pass percentage (GPP) is the predominant metric used for Patient Specific Quality Assurance (PSQA) in radiation therapy. The dimensionality of the measurement geometry in PSQA has evolved from 2D planar to 3D planar, and presently to state-of-the-art 3D volumetric geometry. We aim to critically examine the performance of the three-dimensional gammas vis-à-vis the older gamma metrics of lower dimensionality to determine their mutual fungibility in PSQA, using clinically approved Volumetric Arc Therapy (VMAT) plans.

Decline in fish species diversity due to climatic and anthropogenic factors in Hakaluki Haor, an ecologically critical wetland in northeast Bangladesh.

This study evaluates changes in fish species diversity over time in Hakaluki Haor, an ecologically critical wetland in Bangladesh, and the factors affecting this diversity. Fish species diversity data were collected from fishers using participatory rural appraisal tools and the change in the fish species diversity was determined using Shannon-Wiener, Margalef's Richness and Pielou's Evenness indices. Principal component analysis (PCA) was conducted with a dataset of 150 fishers survey to characterize the major factors responsible for the reduction of fish species diversity.

Achieving equitable uptake of handwashing and sanitation by addressing both supply and demand-based constraints: findings from a randomized controlled trial in rural Bangladesh.

Background: Supply driven programs that are not closely connected to community demand and demand-driven programs that fail to ensure supply both risk worsening inequity. Understanding patterns of uptake of behaviors among the poorest under ideal experimental conditions, such as those of an efficacy trial, can help identify strategies that could be strengthened in routine programmatic conditions for more equitable uptake. WASH Benefits Bangladesh was a randomized controlled efficacy trial that provided free-of cost WASH hardware along with behavior change promotion.

COVID-19 Epidemic in Bangladesh among Rural and Urban Residents: An Online Cross-Sectional Survey of Knowledge, Attitudes, and Practices.

As other nations around the world, Bangladesh is facing enormous challenges with the novel coronavirus (COVID-19) epidemic. To design a prevention and control strategy for this new infectious disease, it is essential to first understand people's knowledge, attitudes, and practices (KAP) regarding COVID-19. This study sought to determine KAP among rural and urban residents as well as predictors of preventive practices associated with COVID-19 in Bangladesh.

Application of Metal-Organic Frameworks in Adsorptive Removal of Organic Contaminants from Water, Fuel and Air.

Currently, our environment is contaminated with various toxic substances. Removal of such hazardous materials from water, air and fuel is important for sustainability. In this minireview, adsorptive removal of organic substances, by using metal-organic frameworks (MOFs), for our safe environment will be discussed.

Retrospective study on performance of constancy check device in Linac beam monitoring using Statistical Process Control.

Aim: To examine the application of Statistical Process Control (SPC) and Ishikawa diagrams for retrospective evaluation of machine Quality Assurance (QA) performance in radiotherapy.

Background: SPC is a popular method for supplementing the performance of QA techniques in healthcare. This work investigates the applicability of SPC techniques and Ishikawa charts in machine QA.

Quantitative assessment of fecal contamination in multiple environmental sample types in urban communities in Dhaka, Bangladesh using SaniPath microbial approach.

Rapid urbanization has led to a growing sanitation crisis in urban areas of Bangladesh and potential exposure to fecal contamination in the urban environment due to inadequate sanitation and poor fecal sludge management. Limited data are available on environmental fecal contamination associated with different exposure pathways in urban Dhaka. We conducted a cross-sectional study to explore the magnitude of fecal contamination in the environment in low-income, high-income, and transient/floating neighborhoods in urban Dhaka.

Bias-reduced and separation-proof GEE with small or sparse longitudinal binary data.

Generalized estimating equation (GEE) is a popular approach for analyzing correlated binary data. However, the problems of separation in GEE are still unknown. The separation created by a covariate often occurs in small correlated binary data and even in large data with rare outcome and/or high intra-cluster correlation and a number of influential covariates.

Parental perceptions of impact of oral disorders on Colombian preschoolers' oral health-related quality of life.

There is no study assessing the impact of dental caries (DC), traumatic dental injuries (TDI) and dental malocclusions (DM) on the oral health-related quality of life (OHRQoL) of preschool children from Spanish-speaking countries in population-based samples. The purpose of this study was to assess the impact of DC, TDI and DM, on Colombian preschool children's OHRQoL through a cross-sectional study. The clinical setting included private and public preschools in Cartagena,Colombia.

Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties.

Sea cucumbers belonging to echinoderm are traditionally used as tonic food in China and other Asian countries. They produce abundant biologically active triterpene glycosides. More than 300 triterpene glycosides have been isolated and characterized from various species of sea cucumbers, which are classified as holostane and nonholostane depending on the presence or absence of a specific structural unit γ(18,20)-lactone in the aglycone.

Metabolites from the Endophytic Fungus Curvularia sp. M12 Act as Motility Inhibitors against Phytophthora capsici Zoospores.

The endophytic fungus Curvularia sp., strain M12, was isolated from a leaf of the medicinal plant Murraya koenigii and cultured on rice medium followed by chemical screening of the culture extract. Chromatographic analysis led to the isolation of four new compounds, murranofuran A (1), murranolide A (2), murranopyrone (3a), and murranoic acid A (4a), along with six known metabolites, N-(2-hydroxy-6-methoxyphenyl)acetamide (5), curvularin (6), (S)-dehydrocurvularin (7), pyrenolide A (8), modiolide A (9), and 8-hydroxy-6-methoxy-3-methylisocoumarin (10).

A New Lactone from Chaetomium globosum Strain M65 that Inhibits the Motility of Zoospores.

In a search for endophytes from medicinal plants of Bangladesh, we isolated the M65 fungal strain from the fruit of Azadirachta indica. Following chemical screening, chromatographic purification of the culture extract of strain M65 led to the isolation of the previously reported lasiodiplodin (2), the known derivative 1, and the new derivative 3a, along with two further known compounds (4 and 5). The new (3R,5R)-5-hydroxylasiodiplodin (3a), the enantiomer of the known (3S,5S)-5-hydroxylasiodiplodin (3b), inhibited the motility of zoospores of a devastating late blight phytopathogen Phytophthora capsici by 100% at a concentration of 10 μg/mL.

Application of Standardized Precipitation Index to assess meteorological drought in Bangladesh.

Bangladesh is one of the vulnerable countries of the world for natural disasters. Drought is one of the common and severe calamities in Bangladesh that causes immense suffering to people in various ways. The present research has been carried out to examine the frequency of meteorological droughts in Bangladesh using the long-term rainfall data of 30 meteorological observatories covering the period of 1948-2011.