Neophobia, conditioned taste aversion and EEG arousal after globus pallidus lesion.

Rats with unilateral or bilateral electrolytic lesions in the globus pallidus (GP) became aphagic and adipsic. Aphagia and adipsia lasted 2-3 days in rats with unilateral lesion, but were more persistent in animals with bilateral lesions. EEG arousal induced by nociceptive stimuli applied to the side of the body contralateral to the unilateral pallidal lesion was of shorter duration than that induced by ipsilateral stimulation; no difference was found between rats injured in left or right (GP).

Cortical control of neurally-mediated arrhythmogenic properties of desacetyl lanatoside C: the role of the posterior hypothalamus.

Functional ablation of the cerebral cortex by cortical spreading depression (CSD) significantly increased the dose of desacetyl lanatoside C required to induce A-V block and ventricular fibrillation. To examine the role of the posterior hypothalamus in the increased resistance of decorticated rats to arrhythmia induced by toxic doses of desacetyl lanatoside C, four groups of animals were injected with this drug: group 1 rats had a craniotomy; group 2 rats had a craniotomy and functional decortication; group 3 rats had a craniotomy and a hypothalamic lesion; and group 4 rats had a craniotomy, hypothalamic lesion and functional decortication. The dose of drug required to induce A-V block and ventricular fibrillation was significantly less in group 1, than in groups 2,3 and 4, and there was no statistically significant difference between these last three groups.