Alpha-fetoprotein (AFP) is a protein similar to serum albumin, primarily produced in the fetal liver and yolk sac, peaking in concentration towards the end of the first trimester before declining after birth.
AFP has three binding pockets for interacting with other biomolecules and features sites for phosphorylation and acetylation, influencing various physiological and pathological processes.
Elevated levels of AFP in the blood are a known biomarker for certain cancers, including yolk sac, embryonal, and hepatocellular carcinoma, and the review discusses its chemical properties, receptors, and clinical significance in cancer treatment.
* Researchers measured the time it took for the worms to become paralyzed and subsequently die, comparing these results to a standard treatment using piperazine citrate.
* The results showed that both extracts from the bark of Tamarindus indica were effective in reducing the time for paralysis and death, supporting its potential use as an anthelmintic agent.