Isolated Corrective Saccades in the Bilateral Posterior Canal Stimulation During the Video Head Impulse Test: A Marker of Central Vestibulopathy?

Objectives: This study aimed to determine if the presence of corrective saccades during video head impulse test (vHIT) stimulation of the bilateral posterior semicircular canals (PSCs) correlated with other vestibular test results, demographics, symptoms, or diagnoses.

Design: This study was a retrospective chart review where 1006 subjects' vHIT records were screened with 17 subjects meeting inclusion criteria for isolated bilateral PSC saccades.

Results: Of the 1006 patients undergoing vHIT testing, only 1.

Proinflammatory Cytokine Profiles in Menière's Disease and Vestibular Migraine.

Objective: To evaluate the levels of inflammatory cytokines and symptom survey scores in patients diagnosed with Menière's disease or vestibular migraine from a single center by a single neurotologist compared to control subjects with no history of dizziness or migraine.

Study Design: Cross-sectional pilot study.

Setting: Single-center tertiary referral center in Charleston, SC.

The placebo effect of sham rhinologic procedures in randomized controlled trials: A systematic review and meta-analysis.

Sham procedures produce a clinically significant impact on patient-reported outcome measures This effect should be considered when designing and interpreting the results of RCTs.

Effects of Body Positioning on Laryngeal Penetration and Aspiration in Children with Unilateral Vocal Cord Paralysis.

Objective: To evaluate laryngeal penetration and aspiration in upright and side-lying positions in children with unilateral vocal cord paralysis (VCP) who underwent modified barium swallow study (MBSS).

Methods: A retrospective chart review (Pro00089051) of pediatric patients who were diagnosed with unilateral VCP and underwent MBSS was performed. Patients were identified using diagnostic code for VCP and based on diagnosis via flexible laryngoscopy.

Characteristics and outcomes of interventions for pediatric laryngomalacia: A systematic review with meta-analysis.

Objectives: To analyze characteristics of children treated for laryngomalacia to determine predictive factors and provide an updated meta-analysis on outcomes.

Methods: A systematic review was conducted according to PRISMA guidelines from inception to May 2, 2023, using CINAHL, PubMed, and Scopus databases. Study screening, data extraction, quality rating, and risk of bias assessment were performed by 2 independent reviewers.

Adult Laryngomalacia: A Scoping Review.

Objective: This review sought to determine the characteristics of adults diagnosed with new onset laryngomalacia including airway symptoms, laryngoscopic findings, treatments, and outcomes. Moreover, we wanted to highlight suspected limitations in the literature.

Data Sources: Studies were identified through CINAHL, Cochrane Review, PubMed, and Scopus published between 1966 and 2023.

The placebo effect in randomized-controlled trials of medical treatments for chronic rhinosinusitis: A systematic review and meta-analysis.

Background: The placebo effect observed in clinical trials evaluating medical treatments for chronic rhinosinusitis (CRS) is not well understood. This systematic review and meta-analysis sought to characterize the placebo effect present within CRS outcomes.

Methods: A systematic review of PubMed, Scopus, and Cumulated Index in Nursing and Allied Health Nursing (CINAHL) was performed.

Editorial: Special Issue on the Epidemiology of Human Papilloma Virus-Associated Oropharyngeal Squamous Cell Carcinoma.

In this Special Issue of , the role of oncogenic human papilloma virus (HPV) with oropharyngeal squamous cell carcinoma is explored […].

Characterization of Glucokinases from Pathogenic Free-Living Amoebae.

Infection with pathogenic free-living amoebae, including Naegleria fowleri, spp., and Balamuthia mandrillaris, can lead to life-threatening illnesses, primarily because of catastrophic central nervous system involvement. Efficacious treatment options for these infections are lacking, and the mortality rate due to infection is high.

A questionnaire-based study of Paediatric Dentists' knowledge of teething signs, symptoms and management.

Introduction: Signs and symptoms attributed to erupting primary teeth are commonly known as "teething". Its existence is controversial with concern that overusing this term might mask other illnesses and some treatments may be unnecessary or harmful. Parents/carers can access over-the-counter remedies and may seek professional advice.

Dual-Stage Picolinic Acid-Derived Inhibitors of .

causes a prevalent human infection for which only the acute stage has an FDA-approved therapy. To find inhibitors of both the acute stage parasites and the persistent cyst stage that causes a chronic infection, we repurposed a compound library containing known inhibitors of parasitic hexokinase, the first step in the glycolysis pathway, along with a larger collection of new structural derivatives. The focused screen of 22 compounds showed a 77% hit rate (>50% multistage inhibition) and revealed a series of aminobenzamide-linked picolinic acids with submicromolar potency against both parasite forms.

Online social media tells a story of , , and (Orthoptera, Tetrigidae), rare Australian pygmy grasshoppers.

Knowledge on the pygmy grasshoppers of Australia is, despite the numerous endemics being described from this unique continent, still scarce. Of interest is the genus group, including genera Storozhenko, 2019, Storozhenko, 2019, Storozhenko, 2019 and Sjöstedt, 1921. The systematic position of this group, currently assigned to Batrachideinae (Bufonidini), is probably not correct.

Teething products may be harmful to health.

Introduction An internet search identified teething powders licensed in the UK containing sucrose and alcohol.Aims To identify current UK guidance on teething and potentially harmful ingredients in teething products.Methods Internet searches identified UK national guidance on teething and evidence on teething interventions.

Exponential tooth decay curve.

Objective: A review of the distribution of d₃mft scores for Wales was undertaken to inform decisions on future reporting of decay experience. Visual examination of data from one survey suggested that caries in Wales is distributed along an exponential decay curve.

Basic Research Design: Weighted d₃mft data from 2007/8, 2011/12 and 2014/15 was utilised.

Genomic Evidence of Widespread Admixture from Polar Bears into Brown Bears during the Last Ice Age.

Recent genomic analyses have provided substantial evidence for past periods of gene flow from polar bears (Ursus maritimus) into Alaskan brown bears (Ursus arctos), with some analyses suggesting a link between climate change and genomic introgression. However, because it has mainly been possible to sample bears from the present day, the timing, frequency, and evolutionary significance of this admixture remains unknown. Here, we analyze genomic DNA from three additional and geographically distinct brown bear populations, including two that lived temporally close to the peak of the last ice age.

Non-intentional farm injury fatalities in NSW, Australia, 2001-2015.

Background: Agriculture is one of the most hazardous industries in Australia. The Australian Centre for Agricultural Health and Safety is the only agency that records all non-intentional injury-related events (work and nonwork) on Australian farms.

Materials And Methods: Drawing on records from the National Coronial Information System, data for New South Wales (NSW), Australia, were analysed to assess cases in the 2001-2015 period.

Trends and Patterns in Unintentional Injury Fatalities in Australian Agriculture.

Agriculture is recognized internationally as a hazardous industry. This article describes the trends and patterns of unintentional farm fatalities in Australia. Data from the National Coronial Information System were analyzed to assess all unintentional farm fatalities for the 2001-2015 period.

The caries experience of 5 year-old children in Scotland in 2013-2014, and in England and Wales in 2014-2015. Reports of cross-sectional dental surveys using BASCD criteria.

Objective: We report the findings from and comment on the surveys of the oral health of 5-year-old children undertaken in Scotland (2013-14), Wales (2014-15) and England (2014-15). This was the fourteenth survey in Scotland since 1988. In England and Wales it is the third survey since 2007 when changes were required in consent arrangements.

What proportion of caries into dentine at age 5 is present at age 3?

Objective: To explore the proportion of decay at age 5 in Wales presenting by and after age 3 years from geographical and deprivation perspectives.

Basic Research Design: Retrospective analysis of data from independent cross-sectional studies of 3-year-olds in early 2013 and 5-year-olds in school year 2014/5. This includes novel graphical presentation of caries at age 3 and estimated 3-5 caries increment at age 5.

Measuring oral health impact among care home residents in Wales.

Objective: To explore inequalities in oral health impact among care home residents using OHIP-14 and ADHS criteria.

Basic Research Design: Cross-sectional survey with structured interview and clinical examination using 2009 ADHS criteria including OHIP-14. Comparisons were made between groups of residents and with findings from the ADHS 2009.

Fatal Incidents in Australia's Older Farmers (2001-2015).

Objectives: This study assesses nonintentional injury deaths of older farmers and the causal agents associated with these fatalities in Australia (2001-2015). It also explores approaches based on the hierarchy of risk controls to reduce fatalities and injuries in this cohort.

Methods: Data on farm-related incidents were sourced from the National Coroners Information System (NCIS) for the study period and coded.

Dentist skill and setting to address dental treatment needs of care home residents in Wales.

Objective: To explore the relationship between treatment plans, complexity anticipated in delivering those plans, and the special care dental skills and settings identified as appropriate.

Background: In older adults, many factors may complicate dental treatment including health and disability problems. Assessment of dental treatment needs amongst care home residents provides information about clinical care required and clinical experience needed for this population.