Publications by authors named "Mona Zhang"
Article Synopsis
- PFAS, particularly PFOA, have been linked to an increased risk of breast cancer, prompting a study using a zebrafish model to explore their toxic effects during breast cancer development.
- The study involved co-implanting human preadipocytes with breast cancer cell lines (MCF-7 and MDA-MB-231) in zebrafish embryos to simulate a realistic tumor microenvironment.
- Results showed that PFOA promoted cell proliferation and migration in MCF-7 cells, enhancing their metastatic potential, while effects on MDA-MB-231 cells were less consistent, highlighting varying responses to PFAS based on cancer cell phenotype.
Background: Patient-oriented research (POR) aligns research with stakeholders' priorities to improve health services and outcomes. Community-based health care settings offer an opportunity to engage stakeholders to determine the most important research topics to them. Our objectives were to identify unanswered questions that stakeholders had regarding any aspect of child and family health and prioritize their 'top 10' questions.
View Article and Find Full Text PDFBackground: The objectives of this systematic review were to synthesize qualitative evidence on the impacts of COVID-19 restrictions on physical activity (PA) for children and youth, and explore factors perceived to influence those impacts.
Methods: Five databases (MEDLINE, Embase, SPORTDiscus, ERIC, and CINAHL) were searched initially in June 2021 and updated in December 2021 to locate qualitative articles considering COVID-19 restrictions and PA for children and youth (≤18 y old), in any setting. Eligibility, quality assessments, and data extraction were completed by 2 independent reviewers.