Publications by authors named "Mona Spiridon"

The use of screen electronic devices in the evening negatively affects sleep. Yet, sleep is known to be essential for brain maturation and a key factor for good academic performance, and thus is particularly critical during childhood and adolescence. Although previous studies reported associations between screen time and sleep impairment, their causal relationship in adolescents remains unclear.

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Prism adaptation does not only induce short-term sensorimotor plasticity, but also longer-term reorganization in the neural representation of space. We used event-related fMRI to study dynamic changes in brain activity during both early and prolonged exposure to visual prisms. Participants performed a pointing task before, during, and after prism exposure.

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How representations of visual objects are maintained across changes in viewpoint is a central issue in visual perception. Whether neural processes underlying view-invariant recognition involve distinct subregions within extrastriate visual cortex for distinct categories of visual objects remains unresolved. We used event-related functional magnetic resonance imaging in 16 healthy volunteers to map visual cortical areas responding to a large set (156) of exemplars from 3 object categories (faces, houses, and chairs), each repeated once after a variable time lag (3-7 intervening stimuli).

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Background: 22q11.2 deletion syndrome (22q11DS) is a neurogenetic syndrome associated with a high rate of psychiatric disorders. Previous research has revealed distinctive cognitive deficits, including impaired face processing.

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Subjects were scanned in a single functional MRI (fMRI) experiment that enabled us to localize cortical regions in each subject in the occipital and temporal lobes that responded significantly in a variety of contrasts: faces>objects, body parts>objects, scenes>objects, objects>scrambled objects, and moving>stationary stimuli. The resulting activation maps were co-registered across subjects using spherical surface coordinates [Fischl et al., Hum Brain Mapp 1999;8:272-284] to produce a "percentage overlap map" indicating the percentage of subjects who showed a significant response for each contrast at each point on the surface.

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We used fMRI to study the distribution of object category information in the ventral visual pathway. Extending the findings of, we find that categories of stimuli can be distinguished by the pattern of activation they elicit across this entire pathway, even when the stimuli within a category differ in viewpoint, exemplar, or image format. However, regions within the ventral visual pathway are neither interchangeable nor equipotential.

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