An immunosensor based on gold nanorods (AuNRs) etchant activity of a metal-organic framework (MOF): MIL-88B(Fe)-reduced graphene oxide (rGMOF) was developed for the determination of prostate-specific antigen (PSA). Several techniques, including FTIR, UV-Vis spectrophotometry, XRD, and electron microscopy, were employed to characterize the MOFs containing iron-oxygen clusters on the surface of reduced graphene oxide. Enzyme mimetic activity of rGMOF before and after bioconjugation with antibodies was calculated as 8.
View Article and Find Full Text PDFWe designed a magneto-plasmonic biosensor for the immunodetection of antigens in minute sample volume. Both spherical gold nanoparticles (AuNP) and magnetic beads (MB) were conjugated to goat anti-rabbit IgG antibody (Ab) capable of recognizing a model target, rabbit IgG (rIgG). The AuNP bioconjugate was used as the optical detection probe while the MB one was used as the capture probe.
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