Prediction of Blood miRNA-mRNA Regulatory Network in Gastric Cancer.

Background: The aim of the study was to suggest a high specific and sensitive blood biomarker for early GC diagnosis.

Methods: the expression data of miRNAs and mRNAs were collected from the blood samples of the GC patients based on literature mining. Bioinformatics tools and databases (PANTHER, TargetScan, miRTarBase, miRDB, STRING, and Cytoscape) were used to predict the regulatory relationship.