Publications by authors named "Mona M El-Ganzoury"
Kawarabi: Administrative Structuring of a Multicenter Research Collaborative to Study Kawasaki Disease in the Arab Countries.
World J Pediatr Congenit Heart Surg
March 2024
Article Synopsis
- - Kawasaki disease (KD) is the leading cause of acquired heart disease in children from developed countries, necessitating detailed studies within Arab nations to enhance diagnosis and care.
- - Kawarabi is a collaborative initiative involving North American and Arab experts aimed at improving knowledge and management of KD and similar conditions, primarily initiated during the COVID-19 pandemic's emergence of multisystem inflammatory syndrome in children.
- - Founded in 2021, Kawarabi has identified gaps in awareness and resources concerning KD in Arab countries, and it has organized educational webinars and meetings to promote better understanding of the disease and its long-term outcomes.
Article Synopsis
- - Kawasaki Disease (KD) remains the leading acquired heart disease in children under five, with limited data available from Arab nations, prompting the creation of the KD Arab Initiative (Kawarabi) in 2021 to enhance research and access to care.
- - A survey conducted across thirteen Arab countries revealed that while access to KD care was generally equal in urban and rural areas for over half of the countries surveyed, many rural areas still experienced significant disparities in healthcare access, especially in mid-size cities.
- - The survey indicated a difference in the quality of medical services for KD, with urban children receiving better care, and highlighted that the availability of intravenous immunoglobulin (IVIG) was critically low in rural and mid-size areas,
Article Synopsis
- Studies on Kawasaki disease in Arab countries show limited data, leading to the formation of the KD Arab Initiative (Kawarabi) consortium for collaborative research.
- An anonymous survey among 19 physicians from 12 institutions revealed that while 79% refer to American Heart Association guidelines, there are significant variations in treatment availability, particularly with intravenous immunoglobulin (IVIG).
- The survey found low awareness of Kawasaki disease among the general population (median score 3) but relatively higher knowledge within the medical community (median score 7), highlighting the need for more proactive collaboration and education.
Objective: The poor preoperative nutritional state of children with congenital heart disease (CHD) is often exacerbated postoperatively. The aim of this study was to evaluate the effect of perioperative 1- versus 2-wk nutritional prehabilitation programs on growth and surgical outcomes in malnourished children with CHD.
Methods: Forty malnourished infants scheduled for elective CHD surgery were randomized to receive either 1 or 2 wk of a nutritional prehabilitation program.
Objective: To evaluate the efficacy and safety of enteral recombinant human granulocyte colony-stimulating factor (rhG-CSF) and recombinant human erythropoietin (rhEPO) in preventing feeding intolerance.
Study Design: An interventional randomized control trial was conducted in 90 preterm infants born at ≤33 weeks gestational age. The neonates were assigned to 4 groups; 20 received rhG-CSF, 20 received rhEPO, 20 received both, and 30 received distilled water (placebo control).
Objectives: To determine the effect of maternal antenatal administration of vitamin K1 on activity level of vitamin K-dependent coagulation factors and on the occurrence of periventricular-intraventricular hemorrhage (PIVH).
Methods: This study was conducted on 90 infants who were classified into; Group A: 30 preterm whose mothers received antenatal vitamin K1, Group B: 30 preterm whose mothers did not receive antenatal vitamin K1, and Group C: 30 healthy full term newborns as a control group. All newborns were subjected to measurement of the activity level of vitamin K-dependent coagulation factors (FII, FVII, FIX and FX).
Objective: to estimate the association between intrauterine fetal growth, evaluated by anthropometric measurements, and biochemical growth factors; IGF-I and IGBP-1 among IDMs.
Methods: Cross-sectional study carried out on 69 full term IDMs who was admitted to neonatal intensive care units, Ain Shams University Hospitals. Clinical examination including anthropometric measurements; birth weight, length, head circumference, mid-arm circumference, skinfold thickness at triceps and subscapular areas and placental weight.
Background. Sensorineural hearing loss after procedures including extracorporeal circulation and hypothermia is greater than general population. Mild hypothermia has a protective role on cochlea; however, deep hypothermia may result in cochlear injury.
View Article and Find Full Text PDFNeonates are susceptible to septicemia secondary to quantitative and qualitative neutrophilic defects. Granulocyte colony-stimulating factor (G-CSF) stimulates myeloid progenitor cell proliferation and induces selective neutrophil functions. The authors aimed to evaluate the effect of G-CSF administration in septic neonates on neutrophil production and CD11b expression.
View Article and Find Full Text PDFBackground: Cardiac malformations in infants of diabetic mothers (IDMs) are five times higher than in normal pregnancies. Insulin-like growth factor-I (IGF-I) is the most important growth factor in utero and is predominantly bound by IGF binding protein-1 (IGFBP-1).
Objective: To examine the echocardiographic findings of neonates of diabetic mothers and the relationship with cord blood IGF-I and IGBP-1.