Publications by authors named "Mona H El-Nagdy"
Scand J Clin Lab Invest
August 2019
Article Synopsis
- SALL4 is a transcription factor that keeps stem cells undifferentiated and is involved in leukemia development, specifically affecting leukemic stem cells.
- The study analyzed SALL4 gene expression in 106 patients with acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) using real-time PCR, finding increased levels in both types of leukemia.
- Higher SALL4 expression in AML patients correlated with worse disease-free survival rates, indicating its potential as a prognostic marker in these leukemias.
