Publications by authors named "Mona Elhelaly"
Article Synopsis
- Highly upregulated in liver cancer (HULC) and myotubularin-related protein 3 (MTMR3) play significant roles in cancer progression, with MTMR3 being a negative autophagy regulator.
- A study involving 245 patients analyzed gene expression levels of HULC and MTMR3 through TaqMan Real-time PCR, finding elevated levels in breast cancer patients compared to controls.
- Results showed a strong association between specific genotypes of MTMR3 and HULC with breast cancer risk, indicating a potential link between these biomarkers and the development of the disease in the Egyptian population.
Background: Oxidative stress is thought to play a significant role in the pathogenesis and severity of COVID-19. Additionally, angiotensin converting enzyme 2 (ACE2) expression may predict the severity and clinical course of COVID-19. Accordingly, the aim of the present study was to evaluate the association of oxidative stress and ACE2 expression with the clinical severity in patients with COVID-19.
View Article and Find Full Text PDFOrganochlorines (OCs) are groups of highly toxic pesticides with known immunotoxicity. The present work aimed to study the potential association between serum residues of OCs and the risk of developing systemic lupus erythematosus (SLE) as well as correlating to the clinical-laboratory manifestations in a sample of Egyptian SLE patients. A cross-sectional study was conducted on 132 patients environmentally exposed to OCs.
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