Publications by authors named "Mona El-Abd"

Background: The final decision to fast or not fast for routine lipid profile examination in a standard, healthy population is unclear. Whereas the United States and European protocols state that fasting for regular lipid analysis is unnecessary, the North American and Chinese guidelines still recommend fasting before routine lipid testing.

Aim: This study aimed to unravel the contradiction between the different protocols of lipid profile testing worldwide and clarify the effect of diet on lipid profile testing only in a regular, healthy population.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the link between the EGF (rs4444903) gene polymorphism and the risk of cholangiocarcinoma (CCA) in Egyptian patients, suggesting that specific genotypes (GG and AG) are associated with higher risks compared to the AA genotype.
  • Results indicate that the G allele is significantly connected to increased CCA risk, though its association is less clear in certain genetic models.
  • Overall, while there is evidence that the EGF rs4444903 polymorphism may contribute to CCA development, it does not appear to impact the disease's severity.
View Article and Find Full Text PDF

Background/objectives: The role of spexin (SPX) in energy metabolism, endocrinal homeostasis, and vasculopathy is emerging. However, scarce data are available about its role in childhood obesity and obesity-related vasculopathy. Hence, we aimed to assess the level of SPX in obese and normal-weight children, and to correlate it with aortic distensibility (AD) and aortic stiffness index (ASI).

View Article and Find Full Text PDF

Aim Of The Study: We aimed to evaluate the association of microRNA-499 rs3746444 polymorphism and biliary atresia (BA) risk and its correlation with clinic-pathologic features of BA.

Material And Methods: This study was performed on 300 Egyptian children (100 BA cases, 100 cases with cholestatic liver diseases other than BA and 100 healthy controls). Routine laboratory investigations, clinical examination and abdominal ultrasound were done.

View Article and Find Full Text PDF