Publications by authors named "Mona E Mahmoud"
Cell Biochem Funct
March 2022
Article Synopsis
- Chronic kidney disease (CKD) involves inflammation and fibrosis, particularly renal fibrosis, which is linked to excessive extracellular matrix production and exposure to harmful substances, with no effective treatments currently available.
- A study was conducted to evaluate vanillin's protective effects against renal injury in rats induced by TAA, with results showing that vanillin significantly improved kidney function and reduced various harmful protein levels associated with inflammation and fibrosis.
- Additionally, vanillin reduced the expression of specific genes and proteins related to kidney injury and fibrosis, and molecular docking analysis indicated strong binding to TGF-β type I receptors, suggesting a potential therapeutic role in renal protection.
