Publications by authors named "Mona Chowdhury"
Context: Human leukocyte antigens (HLAs) have an important role in the determination of susceptibility and resistance to periodontal diseases in humans, which may vary from population to population.
Aims: The aim of this study was to find out the association of HLA Classes I and II genes with chronic periodontitis in East Indian population.
Materials And Methods: In a cross-sectional study design, a total of sixty participants of chronic periodontitis (CP) (mean age: 44.
Article Synopsis
- The study investigates the relationship between genetic markers (HLA) and immune cell dysfunction in aggressive periodontitis (AP), comparing it to chronic periodontitis (CP) and healthy controls.
- The research involved 45 participants divided into three groups (healthy, CP, and AP) to analyze various immune parameters.
- Findings suggest a higher frequency of specific HLA types and blood group AB in AP subjects, along with significantly altered immune responses, indicating a possible link between genetic factors and periodontal disease severity.