Publications by authors named "Mona Alasmi"
Background: Functional constipation (FC) is a common condition in children, and information on the clinical characteristics of FC in Saudi children is scarce.
Objective: Describe the clinical profile of FC in Saudi children.
Design: Retrospective.
Article Synopsis
- This report investigates the types and amounts of viruses present in the guts of healthy Saudi children to better understand their health impact.
- The study involved analyzing stool samples from 20 children in Riyadh, identifying that the Caudovirales order was the most abundant, particularly the Enterobacteria phages.
- Results indicate significant differences in the gut virome of these children compared to existing literature, highlighting the need for further research with larger populations to explore the implications for health and disease treatment.
Background: Intestinal dysbiosis has been reported to be associated with celiac disease (CeD) in Western populations but little is known in other populations who have different dietary lifestyle and genetic background. The purpose of this study was to determine whether a different microbiota profile is associated with CeD in children in Saudi Arabia.
Results: Forty children with CeD, 20 healthy controls, and 19 non-CeD controls were enrolled.
Article Synopsis
- This study aimed to analyze the intestinal microbiota in healthy Saudi children to enhance understanding of its role in health and disease.
- Researchers collected and analyzed stool samples from 20 Saudi school children, identifying the most prevalent bacterial phyla and genera, with Firmicutes, Bacteroidetes, and Actinobacteria being the most abundant.
- The findings highlight that the microbiome composition in healthy Saudi children differs from other populations, prompting the need for further research to explore these variations and their implications for health.
Article Synopsis
- * This study analyzed the viral profiles from fecal and mucosal samples of 40 children with new-onset CeD and 39 healthy controls, finding distinct viral dysbiosis in the CeD group.
- * Although specific viral species were found to be more or less abundant in the fecal samples of children with CeD, mucosal samples did not show significant associations, highlighting the complexity of viral interactions in gut health and the need for more research.
Background: Although intestinal fungi are known to interact with the immune system, the relationship between intestinal fungi and childhood celiac disease (CeD), an immune-mediated condition, has rarely been reported.
Aims: The aim of this study was to describe gut fungal profiles in a cohort of children with new-onset CeD.
Methods: Mucosal and fecal samples were collected from children with CeD and controls and subjected to metagenomics analysis of fungal microbiota communities.
Prader-Willi syndrome (PWS) is a rare genetic disorder caused by deletion or unexpression of the chromosome 15 (q 11-13). Symptomatologies include hypotonia, hyperphagia, cognitive impairment, and characteristic dysmorphic profile. Here, we report a 4-year-old boy with PWS who presented with complications of congenital hepatic fibrosis.
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