Optimization and Validation of an Analytical Method for the Determination of Some Trace and Toxic Elements in Canned Fruit Juices Using Quadrupole Inductively Coupled Plasma Mass Spectrometer.

There is increasing concern about the health effects on humans due to continuous consumption of fruit juices contaminated with metals. Quadrupole inductively coupled mass spectrometry (Q-ICP-MS) was optimized, validated, and applied in routine analysis for determination of As, Pb, Cd, Sb, Hg, Cu, Zn, Fe, Al, Cr, Sn, Co, Mn, and Ni in fruit juice beverages. Several validation parameters, such as detection limits (DLs), quantification limits, linearity, accuracy, and measurement uncertainty (MU), were studied under optimized Q-ICP-MS conditions.