Publications by authors named "Mona A Elshafie"

Introduction: The utility of Circumferential Resection Margin (CRM) status in predicting prognosis in oesophageal cancer is controversial, with different definitions used by the College of American Pathologists and the Royal College of Pathologists. We aimed to determine prognostic significance of CRM involvement and evaluate which system is the best predictor of prognosis.

Methods: A cohort of 390 patients who had potentially curative oesophagectomy (- + neoadjuvant chemotherapy) were analysed.

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Background: Community-acquired pneumonia (CAP) is one of the five leading causes of death among children in developing countries, accounting for approximately three million deaths per year. Identification of the modifiable risk factors of CAP may help to reduce the burden of this disease. In this study, the impact of the socioeconomic status (SES) on the severity and outcome of CAP among Egyptian children was studied.

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Article Synopsis
  • This study investigates the trace element (TE) status in 80 obese Egyptian children compared to 80 healthy non-obese children, focusing on elements like zinc, copper, selenium, iron, and chromium, and their relationship with metabolic risk factors.
  • Results indicate that obese children had significantly lower levels of zinc, selenium, and iron, while copper levels were higher, alongside significant correlations between zinc, leptin levels, and lipid profiles.
  • The findings suggest that deficiencies in certain trace elements could contribute to obesity in children, highlighting the need for further research on their role in obesity-related diseases.
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Background: Leptin serves as a signal to the central nervous system with information on the critical amount of adipose tissue stores that is necessary for activation of the hypothalamic-pituitary-ovarian axis.

Objectives: To document the histological and ultrastructural changes that occur in the ovarian follicles of immature albino rats treated with leptin when compared with controls. Furthermore, the endometrial histological and immunohistochemical, and vaginal cytological changes suggestive of ovulation were assessed.

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