Laser Interstitial Thermal Therapy for the Treatment of Primary and Metastatic Brain Tumors: A Systematic Review and Meta-Analysis.

Background: Laser interstitial thermal therapy (LITT) is a minimally invasive treatment option for intracranial tumors that are challenging to treat via traditional methods; however, its safety and efficacy are not yet well validated in the literature. The objectives of the study were to assess the available evidence of the indications and adverse events (AEs) of LITT and 1-year progression-free survival and 1-year overall survival in the treatment of primary and secondary brain tumors.

Methods: A comprehensive literature search was conducted through the databases PubMed, Embase, and the Cochrane Library until October 2021.

Effect of endocrine treatment on voiding and prostate size in men with prostate cancer: a long-term prospective study.

Objective: The aim of this study was to assess and quantify changes in voiding parameters and prostate size in men with prostate cancer from before the start of endocrine treatment and during long-term follow-up.

Material And Methods: Seventy-seven patients were recruited from three clinics and followed prospectively until death, clinical deterioration making the patient unfit for participation, or the end of the study. Median age was 74 (range 54-85) years, and the median follow-up was 18 (3-90) months.

Prediction of survival of metastatic prostate cancer based on early serial measurements of prostate specific antigen and alkaline phosphatase.

Purpose: We determined how serial measurements of prostate specific antigen and alkaline phosphatase can be used to predict survival early in the course of hormone treated metastatic prostate cancer.

Materials And Methods: The study was based on a prospective randomized trial of 915 patients with metastatic prostate carcinoma designed to compare parenteral estrogen (polyestradiol phosphate) vs total androgen blockade. We included 697 men who survived at least 6 months and had complete serial measurements of prostate specific antigen and alkaline phosphatase.

Validity of a self-administered questionnaire, with reference to a clinical stress urinary incontinence test.

Objective: To estimate the criterion validity of a self-administered questionnaire on urinary incontinence (UI) using a clinical stress UI test as reference.

Material And Methods: A total of 4710 women aged 20-59 years randomly selected from the municipalities of Aarhus and Randers (Denmark) participated in a population survey on UI. A sub-sample of 96 women stratified by the duration and frequency of UI answered an assisted, self-administered questionnaire concerning UI during the preceding 6 months.

[Development of an Internet search strategy to identify new medical technologies in prostate cancer].

Introduction: Technological change is rapid in medicine. The Internet is becoming more and more important as a source of keeping abreast of technological change, but tools to aid clinicians in finding relevant information on the Internet are lacking. The objective of this project was to develop an Internet search strategy to identify new technologies for the treatment of localised prostate cancer.

Risk of postpartum urinary incontinence associated with pregnancy and mode of delivery.

Aim: The aim was to estimate the postpartum urinary incontinence (PP UI) impact of precursory UI during pregnancy (PR UI) and delivery performed by cesarean section (CS) vs. vaginal childbirth (VC).

Methods: Among the members of two population samples, in total 8610 women aged 20-59 years, 1232 had their first childbirth and 642 their second childbirth within 13-120 months prior to responding to a questionnaire that included information on PR UI occurrence, mode of delivery and PP UI occurrence.

Status of pretreatment evaluation, treatment and follow-up regimens for renal cell carcinoma in the Nordic countries.

Objective: One prerequisite for performing multicentre studies is that the clinical handling of the patients must be uniform. We therefore evaluated possible differences in pretreatment evaluation, surgical treatment and follow-up regimes between the Nordic countries and between the different departments that performed nephrectomy due to renal cell carcinoma.

Material And Methods: A questionnaire comprising 21 different questions was sent to all hospitals in the five Nordic countries performing nephrectomy.

Postpartum urinary incontinence.

Background: The aim of the present study was to identify prepregnancy, pregnancy and delivery correlates of urinary incontinence postpartum (PP UI) as reported by women in a cross-sectional population sample.

Methods: A questionnaire-based cross-sectional survey was carried out in 1998 in a random population sample of 3900 20- to 59-year-old women. The present study includes 376 women who had their last delivery during 1993-96.

Menstrual cycle, female hormone use and urinary incontinence in premenopausal women.

Our aim was to study the association between menstrual cycle characteristics, the use of female hormones and urinary incontinence (UI) in an age-stratified random population sample of 2158 premenopausal women who answered a questionnaire on urinary incontinence. Episodes of UI during 1997 were reported by 18.3% and one or more episodes of UI the preceding year by 3.

[Spondylodiscitis as a complication to ultrasound-guided transrectal prostatic biopsy].

We report a case of spondylodiscitis and psoas abscess induced by transrectal ultrasound-guided prostatic biopsy in a 70-year-old man. Multi-resistant E. coli was cultured, and the patient was cured after several trials with antibiotic treatments.

Neoadjuvant chemotherapy with cisplatin and methotrexate in patients with muscle-invasive bladder tumours.

This prospective, randomized study based on two associated trials was designed to evaluate the effect of neoadjuvant chemotherapy with cisplatin and methotrexate with folinic acid rescue or no chemotherapy prior to local treatment in patients with T2-T4b, NX-3, MO transitional cell carcinoma of the bladder. In the first trial, local treatment consisted of cystectomy (DAVECA 8901) and in the other trial the treatment was radiotherapy (DAVECA 8902); 153 eligible patients were randomized. The majority of the patients (89%) completed the protocol.

Correlates of urinary incontinence in pregnancy.

In a population sample, the period prevalence of urinary incontinence (UI) during pregnancy was found to be 19.9% and 24.1% among 352 nulliparous and 290 primiparous women, respectively.

Does urinary incontinence occurrence depend on the menstrual cycle phase?

Background: The aim was to study an eventual co-variation of menstrual cycle progression and urinary incontinence (UI) occurrence in 20-54-year-old-women, who have regular menstrual cycles, which are not influenced by exogenous sex hormones.

Methods: An age-stratified random sample of of 3900 women, aged 20-59 years, answered a questionnaire on UI. The present analysis included 821 women, who reported regular menstrual cycles un-intervened by sex hormone intake.

[Urinary incontinence and pregnancy, vaginal childbirth and obstetric interventions].

The aim was to examine the association between pregnancy, vaginal childbirth (VC) and obstetric techniques, and the prevalence of urinary incontinence (UI). A cross-sectional survey enrolled a random population sample of 6240 women aged 20-59 years, who were mailed a self-administered questionnaire on UI and, among other things, experience of VC and obstetric intervention. More than 75% responded.

Cigarette smoking, N-acetyltransferase 2 acetylation status, and bladder cancer risk: a case-series meta-analysis of a gene-environment interaction.

Tobacco use is an established cause of bladder cancer. The ability to detoxify aromatic amines, which are present in tobacco and are potent bladder carcinogens, is compromised in persons with the N-acetyltransferase 2 slow acetylation polymorphism. The relationship of cigarette smoking with bladder cancer risk therefore has been hypothesized to be stronger among slow acetylators.

[Bladder tumor antigen test versus urinary cytology in patients with bladder tumors].

The value of the BARD bladder tumour antigen (BTA) test for the diagnosis of bladder tumour was compared to urinary cytology. A total of 60 patients with bladder tumours (Category Ta: 39 patients and Category T1-4: 21 patients) were investigated. Urinary cytology was found to be more sensitive than the BTA test.

Prevalent urinary incontinence as a correlate of pregnancy, vaginal childbirth, and obstetric techniques.

Objectives: This study examined the association between pregnancy, vaginal childbirth and obstetric techniques, and the prevalence of urinary incontinence among adult women aged 20 to 59 years.

Methods: A cross-sectional survey enrolled a random sample of 6240 women aged 20 to 59 years who were mailed a self-administered questionnaire focusing on urinary incontinence and other health variables. More than 75% of the women responded.

The International Continence Society (ICS) incontinence definition: is the social and hygienic aspect appropriate for etiologic research?

Objective: To investigate the effect of applying a problem assessment versus a pure symptom urinary incontinence (UI) caseness definition in etiologic research.

Subjects: A random population sample of 2613 women aged 30-59 years, who responded to a postal questionnaire. MAIN PARAMETERS: One-year period prevalence of the symptom of stress UI; UI assessed by the woman to be a social and/or hygienic problem; childbirth and history of abdominal, gynecological, obstetric or urologic surgery.

Estramustine phosphate versus placebo as second line treatment after orchiectomy in patients with metastatic prostate cancer: DAPROCA study 9002. Danish Prostatic Cancer Group.

Purpose: We compared the effect of 560 mg. estramustine phosphate daily to placebo as a supplement to standard palliative therapy in patients with progressive disease after bilateral orchiectomy as first line therapy for metastatic prostate cancer.

Materials And Methods: In a double-blind multicenter study 131 patients with progressing metastatic hormone refractory prostate cancer were randomized to receive 280 mg.

[Overweight and urinary incontinence in women].

The aim was to study the possible role of obesity in adult female urinary incontinence (UI) etiology. A random population sample of 3114 women aged 30-59 were sent a postal questionnaire concerning urinary incontinence and, among other things, body weight and height. The overall response rate was 85%, and the present analysis comprises 2589 women who gave information about their body weight and height.

The role of haematuria in the diagnosis of blunt renal trauma.

In order to reevaluate the indications for an acute excretory urography (IPV) after blunt renal trauma, with special emphasis on the degree of haematuria, the medical records of 114 patients admitted to The Department of Urology, Odense University Hospital during a 10 year period were reviewed. Fourteen cases of major renal damage were revealed. Thirteen of these patients had macroscopic haematuria.

How do we follow patients with Ta grade 1-111 bladder tumors in Denmark?

A questionnaire on the follow-up regimens for Ta grade I-III bladder tumors in Denmark was mailed to 54 urological and surgical departments. Reply rate was 87%. Most patients were followed in out-patient clinics.

Open versus laparoscopic diagnostic pelvic lymphadenectomy.

In the staging of locally advanced bladder cancer and localized prostate cancer 22 consecutive patients underwent open pelvic lymphadenectomy and 9 consecutive patients underwent laparoscopic pelvic lymphadenectomy. The two operations were compared with number of lymph nodes removed, operative time, hospital stay, and postoperative complications. By the open and laparoscopic surgery in average 5.