[Estimate of the dose in the marrow and the gonads of patients undergoing neoplastic treatment with telecobalt therapy (author's transl)].

Measurements of the doses were carried out on phantoms in order to determine the dose in the marrow and gonads of patients undergoing radio-therapeutic treatment with telecobalt therapy with fixed fields. On average, the dose in the marrow for each treatment resulted to be 2.35 Gy in the male and 5.

Biosynthesis of vitamin B12: nature of the volatile fragment generated during formation of the corrin ring system.

It is shown with the help of radiolabeled substrates that biological formation of the corrin ligand system of cobyrinic acid is linked with the release of an equivalent of acetic acid from a hydroporphinoid precursor in which the C-20 atom has undergone methylation prior to its excision from the macrocycle.

[Determination of the genetically significant dose from x-ray diagnosis in the Province of Varese (author's transl)].

The genetically significant dose in the population of Varese Province (about 700,000 inhabitants) from X-ray diagnosis in 1972 has been estimated. The methods adopted and data utilized for the estimate are indicated. Results are discussed in view of the possibility of reducing doses.

[Photographic dosimetry in irradiation of the mediastinum (author's transl)].

Photographic dosimetry was used to ascertain the space distribution of the dose in mediastinal irradiation with sagittal median fields by means of cobalt therapy; the discrepancy between values in tissue-equivalent dummy and homogeneous dummy was minor and is discussed; comparisons are also made with computer values.

[First attempt at evaluating the overall risk induced in the diagnostic use of radionuclides (author's transl)].

An attempt to evaluate the total radiation risk caused by the diagnostic use of radionuclides was made. The estimate was based on the calculation of the genetically significant dose the mean dose in the bone marrow and the dose in the whole body and in the organs which accumulate the radionuclides. The statistical data were furnished by the nuclear medicine service of the Province of Varese.

[Distribution of dosage and estimation of dosage absorbed by critical organs in the fields of irradiation of lymphomas].

Dose distribution in blanket irradiation was determined using the photodensitometer in a life-size dummy; doses in critical tissues (especially heart, spinal cord, bone marrow) are discussed with reference to likely biological risks.

The renal plasma flow and glomerular filtration rate as estimated through double radiocompound renography.

In order to estimate the renal plasma flow and glomerular filtration rate during the course of renography, a method was developed using simultaneously 131I Hippuran and 169Yb DTPA. First results obtained in a survey of approximately 200 patients are encouraging. The method permits an accurate evaluation of the renal function.