Doxycycline's effect on ocular angiogenesis: an in vivo analysis.

Purpose: To determine the in vivo effect of doxycycline on choroidal angiogenesis and pterygium growth by using a choroidal neovascular (CNV) murine model, a directed in vivo angiogenesis assay (DIVAA) and a pterygium murine model.

Design: Experimental study.

Participants: Three murine models were investigated with 4 mice minimum per group and 22 maximum per group.