Relationship between COVID-19 and orofacial clefts.

The work presents the connection between the infection of COVID-19 during pregnancy and non-syndromic orofacial clefts (NSOFC). Aim of the study was to compare the incidence of COVID-19 disease during mother´s pregnancy between a group of the children with NSOFC and a control group of the children without NSOFC. COVID-19 was confirmed by polymerase chain reaction (PCR) test.

[Postoperative accelerated partial radiotherapy for breast cancer].

Background: Interstitial accelerated partial breast irradiation is generally limited to patients with extremely low risk of local recurrence.

Materials And Methods: Between 2004 and 2008, 53 women in the early-stage of breast cancer were treated with multicatheter interstitial brachytherapy in very short general anaesthesia. All patients had T1 (1-22 mm) tumour with no positive auxiliary node and with negative surgical margins.

[Advanced esophageal carcinoma recanalization].

Advanced esophageal carcinoma has poor prognosis with 5-year survival of less than 20%. This poor prognosis is the same for squamous cell carcinoma and adenocarcinoma. Surgical therapy, external radiation and chemotherapy with curative intent are usually impossible because of the advanced disease.

Occurrence of neoclassical facial canons in Caucasian primary school pupils and university students.

Introduction: The study concentrates on nine neoclassical facial references, canons.

Sample And Methods: These neoclassical canons are studied and compared in two groups of young Caucasian population as follows: 160 students were studied, namely 60 primary school boys at the age of seven and 100 young men at the age ranging from 22 to 25 studying at the Comenius University and Slovak Technical University in Bratislava. The following anthropometric parameters were measured: ten heights, five widths, and two angles.

Coxsackie viral infection and orofacial cleft.

The incidence of orofacial cleft (OC) in newborns was compared with the occurrence of virus-neutralizing antibodies to coxsackie viruses in the serum of newborns and their mothers. No significant difference was found when comparing the seropositivity rates between the group of patients and the control group of healthy newborns. If the patients were divided according to the place of residence however, marked differences occurred between the regions.

Orofacial clefts and their influence on chosen anthropometric parameters of craniofacial part children at the age of eight.

The aim of this study was to choose and to measure craniofacial parameters that were expected to be influenced by cleft defects. Eight-year-old children (both boys and girls) with operated clefts (15 antropometric parameters) were measured. The measurements were carried out at the Department of Reconstructive Surgery, Hospital Ruzinov, Bratislava.

Serum markers of liver fibrogenesis, and liver histology findings in patients with chronic liver diseases.

Aim Of The Study: Investigation of the relationships between the grade and stage of chronic liver diseases irrespective of their etiology using some novel serum markers of liver fibrogenesis, the "classical" serum markers of liver necro-inflammatory injury (such as transaminases), and the histomorphological evaluation of liver biopsies.

Methods: Markers of liver fibrogenesis: serum metalloproteinase 1 (MMP-1), tissue inhibitor of MMP-1 (TIMP-1), and N-terminal propeptide of the procollagen III (PIIINP); "liver function tests" (LFTs): bilirubin, transaminases ALT, AST; ALP, GMT; and liver morphology findings: necro-inflammatory activity, fibrosis; were studied in the series of 32, 'naive', i.e.

[Cephalometric analysis of distance x-ray images in children with orofacial clefts].

The authors with the help of cephalometric RTG analysis study the changes of facial skeleton in children with orofacial clefts and the treatment results. Cephalometric analysis was performed on distance X-rays in patients with orofacial clefts from the whole Slovak republic in the number of 178, with age of 7.8 and 9 years.

[Relation between toxoplasmosis and orofacial clefts in children].

The authors performed a serological observation of toxoplasmosis by using the methods of IFT, CFT and ELISA in 118 mothers and their children with orofacial clefts. The results were compared with those gained in the control group of healthy mothers and their children. Titre means of toxoplasma antibodies in inflicted mothers and their children were higher than in the control group.

Teratogenicity of cyclophosphamide in New Zealand white rabbits.

Pregnant rabbit does received daily oral doses of 6.2 or 18.6 mg/kg cyclophosphamide (CP) on days 6-20 of gestation.

[Prenatal virus infections and orofacial clefts].

A potential teratogenic activity of virus infections caused by the viruses of rubella, influenza, parotitis, hepatitis B, cytomegalovirus and the Epstein-Barr virus was investigated. Specific antibodies against these viruses were examined serologically in children with orofacial clefts and in their mothers and the results were compared with those obtained in control children and their mothers. Different micromethods were used in performing the examinations (ELISA, RIA, NIR, KFR, HIT).