Lipid Keratopathy: Histopathology, Major Differential Diagnoses and The Importance of Clinical Correlation.

Lipid keratopathy (LK) is a rare ophthalmological condition characterized by a progressive reduction in visual acuity caused by corneal opacification due to central lipid accumulation. LK is characterized by lipid deposits, cholesterol clefts, and neovascularization (NV) leading to disruption in corneal optical quality. LK classification includes a primary and secondary form which depend on pre-existing corneal or systemic disorders and the evidence of NV.

A Uniquely Altered Oral Microbiome Composition Was Observed in Pregnant Rats With Induced Periodontal Disease.

is an anaerobic bacterium commonly found in the oral cavity and associated with the development of periodontal disease. has also been linked to several systemic vascular and inflammatory diseases including poor pregnancy outcomes. Little is known about the changes in the oral flora during pregnancy in connection to infection.

and adverse pregnancy outcome.

is a Gram-negative, anaerobic bacterium considered to be an important pathogen of periodontal disease that is also implicated in adverse pregnancy outcome (APO). Until recently, our understanding of the role of in APO has been limited and sometimes contradictory. The purpose of this review is to provide an overview of past and current research on that addresses some of the controversies concerning the role of this organism in the pathogenesis of APO.