Clinical Utility of Neurophysiologic Classification (and Declassification) of Myoclonus.

Background: Movement clinical neurophysiology studies can distinguish myoclonus, tremor, and other jerky movements; however, there has been limited demonstration of their real-world clinical impact.

Objective: The aim was to investigate movement study utility in clarifying movement classification and guiding patient management.

Method: A retrospective study of myoclonus-related movement studies was performed.

Safety of dofetilide in stable patients and investigating traits of susceptibility to torsade de pointes.

Background: Atrial fibrillation is the most prevalent cardiac arrhythmia, presenting symptomatic patients with diminished quality of life and worsening of heart failure. Dofetilide, a class 3 antiarrhythmic agent, is a proven and safe rhythm control medication. Initial risk of QT prolongation leading to torsade de pointes (TdP) necessitates a standard protocol mandating hospitalization for three days for initiation.

Medical Students as Teachers: A Student-Led Course in Developing Teaching Skills.

Students as Teachers is a 7-month student-led elective that equips first- and second-year medical students with teaching skills. Pre- and post-course surveys measured participants' knowledge and confidence level in the course's learning objectives such as creating lesson plans, engaging learners, and assessing understanding. Eleven students participated in the course and 10 students completed the pre- and post-course surveys.

Safety and effectiveness of transsplenic access for portal venous interventions: a single-center retrospective study.

Purpose: To assess the safety and effectiveness of percutaneous transsplenic access (PTSA) for portal vein (PV) interventions among patients with PV disease.

Materials And Methods: Adult patients with PV disease were enrolled if they required percutaneous catheterization for PV angioplasty, embolization, thrombectomy, variceal embolization, or transjugular intrahepatic portosystemic shunt (TIPS) placement for a difficult TIPS or recanalization of a chronically occluded PV. The procedures were performed between January 2018 and January 2023.

Geographic Proximity of Medical Students to PM&R Residency Programs Is Associated With Increased Match Rates Into PM&R.

Despite the growing popularity of physical medicine and rehabilitation as a specialty among medical students, meaningful experiences and mentorship can be challenging to obtain and may significantly vary depending on opportunities available to interact with physiatrists. This study explores the association between the geographic proximity of physical medicine and rehabilitation residency programs to medical schools and the match rate of medical students into physical medicine and rehabilitation from 2019 to 2021. Data on US medical schools, graduates, and physical medicine and rehabilitation residency programs were collected from publicly available sources, and a sample of 1193 physical medicine and rehabilitation residents from US medical schools was analyzed using a one-sample proportion test.

Disproportionately high aortic valve calcium scores in atrial fibrillation: implications for transcatheter aortic valve replacement.

Aims: Doppler mean gradient (MG) can underestimate aortic stenosis (AS) severity in patients with atrial fibrillation (AF) compared with patients with sinus rhythm (SR), potentially delaying intervention in AF. This study compared outcomes in patients with AF and SR following transcatheter aortic valve replacement (TAVR) and investigated delay in TAVR based on computed tomography aortic valve calcium score (AVCS).

Methods And Results: Patients who underwent TAVR from 2013 to 2017 for native valve severe AS were identified from an institutional database.

A Holistic Evaluation of Multivariate Statistical Process Monitoring in a Biological and Membrane Treatment System.

Unsupervised process monitoring for fault detection and data cleaning is underdeveloped for municipal wastewater treatment plants (WWTPs) due to the complexity and volume of data produced by sensors, equipment, and control systems. The goal of this work is to extensively test and tune an unsupervised process monitoring method that can promptly identify faults in a full-scale decentralized WWTP prior to significant system changes. Adaptive dynamic principal component analysis (AD-PCA) is a dimension reduction method modified to address autocorrelation and nonstationarity in multivariate processes and is evaluated in this work for its ability to continuously detect drift, shift, and spike faults.

Outpatient Motor Retraining for Functional Movement Disorder: Predictors of a Favorable Short-Term Response.

Background: Treating functional movement disorder (FMD) with motor retraining is effective but resource intensive.

Objectives: Identify patient, disease, and program variables associated with favorable treatment outcomes.

Methods: Retrospective review of the 1 week intensive outpatient FMD program at Mayo Clinic in Minnesota from February 2019 to August 2021.

Systematic Identification of Copositivity Groups in Standard Series Patch Testing Through Hierarchical Clustering.

Importance: Patients are frequently copositive for multiple allergens simultaneously, either due to chemical similarity or simultaneous sensitization. A better understanding of copositivity groups would help guide contact avoidance.

Objective: To use patient data to systematically determine copositivity groups in the Mayo Clinic Standard Series.

Effects of Patient Demographics and Examination Factors on Patient Experience in Outpatient MRI Appointments.

Objective: The objective of this article is to describe the effects of patient demographics and examination factors on patient-reported experience in outpatient MRI examinations.

Methods: This institutional review board-waived, HIPPA-compliant quality improvement study evaluated outpatient MRI appointments from March 2021 to January 2022 using a postappointment survey consisting of a 5-point emoji scale and text-based feedback. Patient demographics and examination information were extracted from electronic medical records.

Who Is Most Burdened in Health Care? An Analysis of Responses to the ICAN Discussion Aid.

Objective: To create a model based on patients' characteristics that can predict the number of burdens reported using the ICAN Discussion Aid, to target use of this tool to patients likeliest to benefit.

Patients And Methods: Six hundred thirty-five patients (aged ≥18 years) completed the ICAN Discussion Aid at a Scottsdale, Arizona, family medicine clinic. Patient characteristics were gathered from their health records.

Resident factors associated with American board of internal medicine certification exam failure.

Introduction: Performance on the certifying examinations such as the American Board of Internal Medicine Certification Exam (ABIM-CE) is of great interest to residents and their residency programs. Identification of factors associated with certification exam result may allow residency programs to recognize and intervene for residents at risk of failing. Despite this, residency programs have few evidence-based predictors of certification exam outcome.

Fluconazole Failure in the Treatment of Coccidioidal Meningitis.

Introduction: Coccidioidal meningitis (CM) is the most lethal form of disseminated coccidioidomycosis. Current guidelines recommend fluconazole as initial therapy but there has been a paucity of data regarding failure of fluconazole and optimal fluconazole dosage in the treatment of CM. We conducted this study to understand risk factors for fluconazole failure.

Quantity and duration of exposure to general anesthesia for pediatric patients with retinoblastoma.

Purpose: To quantify the duration of anesthesia required for optimal management of retinoblastoma (Rb), stratified by clinical factors.

Methods: The medical records of Rb patients treated at Phoenix Children's Hospital between January 2011 and January 2022 were reviewed retrospectively. Demographic, tumor, and treatment data were collected.