Gender Minority Stress, Support, and Inflammation in Transgender and Gender-Nonconforming Youth.

Transgender and gender-nonconforming (TGNC) youth often report higher rates of chronic social stressors such as victimization, discrimination, and rejection. Some of these gender-based stressors may have long-range physical health consequences through inflammation pathways. This study evaluates the feasibility and acceptability of adding biological measures of inflammation to an ongoing prospective clinical study of TGNC youth (ages 9-20 years), initiating affirming medical therapy at a large, urban children's hospital (=56).

Diurnal cortisol slopes and mental and physical health outcomes: A systematic review and meta-analysis.

Changes in levels of the stress-sensitive hormone cortisol from morning to evening are referred to as diurnal cortisol slopes. Flatter diurnal cortisol slopes have been proposed as a mediator between chronic psychosocial stress and poor mental and physical health outcomes in past theory and research. Surprisingly, neither a systematic nor a meta-analytic review of associations between diurnal cortisol slopes and health has been conducted to date, despite extensive literature on the topic.

Cortisol responses to a group public speaking task for adolescents: variations by age, gender, and race.

Laboratory social stress tests involving public speaking challenges are widely used for eliciting an acute stress response in older children, adolescents, and adults. Recently, a group protocol for a social stress test (the Trier Social Stress Test for Groups, TSST-G) was shown to be effective in adults and is dramatically less time-consuming and resource-intensive compared to the single-subject version of the task. The present study sought to test the feasibility and effectiveness of an adapted group public speaking task conducted with a racially diverse, urban sample of U.