Sexual absorption of vaginal progesterone: a randomized control trial.

Objective. To determine if sexual intercourse reduces absorption of vaginal progesterone gel in women and to determine if progesterone is absorbed by the male during intercourse. Study Design.

Molecular evaluation of proliferative-phase endometrium may provide insight about the underlying causes of infertility in women with endometriosis.

Purpose: To determine if endometrial gene expression is different in women with endometriosis-related infertility and fertile women.

Methods: Prospective study of mid-follicular phase endometrium in 47 subjects in two phases: microarray study of 10 infertile women with endometriosis and five fertile controls, and a quantitative real-time PCR (qRT-PCR) study of 27 infertile women with endometriosis and 15 fertile controls. Gene expression was determined by DNA microarray, and qRT-PCR used for 12 "promising" genes based on the microarray analysis.

Antenatal sexually transmitted infection screening in private and indigent clinics in a community hospital system.

Objective: To determine whether clinics that serve indigent patients demonstrate equal compliance with sexually transmitted infection testing guidelines when compared with private clinics.

Study Design: One hundred eighty-three women were divided into cohorts based on whether they received prenatal care at a private or indigent clinic. Timing of required antenatal sexually transmitted infection screening was collected for 8 tests and compliance scores were calculated.

Preventing excessive weight gain during pregnancy through dietary and lifestyle counseling: a randomized controlled trial.

Objective: To estimate whether an organized, consistent program of dietary and lifestyle counseling prevents excessive weight gain in pregnancy.

Methods: This randomized controlled trial assigned women to receive either an organized, consistent program of intensive dietary and lifestyle counseling or routine prenatal care. The primary study outcome was the proportion of patients whose gestational weight gain was within the Institute of Medicine (IOM) guidelines.

Absorption of vaginal estrogen cream during sexual intercourse: a prospective, randomized, controlled trial.

Objective: To determine if intercourse changed serum estradiol levels in women using vaginal E2 cream or in their male partners.

Study Design: Prospective, randomized, placebo-controlled, crossover, blinded study of 10 postmenopausal women and their male sexual partners. Subjects were randomized to estradiol or placebo cream and intercourse, then crossed over after 7-14 days.

Ultrasound-directed transvaginal myolysis: preclinical studies.

The ultimate goal is to develop a safe vaginal ultrasound-directed myolysis needle to treat uterine myomas. The specific preclinical study objective was to determine the optimal power to coagulate myomas in hysterectomy specimens with a prototype needle in a prospective preclinical study with an echogenic insulated needle electrode. In phase I of the study, myolysis was performed with ultrasound guidance at various powers and times.

Patient satisfaction with 3 methods of postpartum contraceptive counseling: a randomized, prospective trial.

Objective: To compare patient satisfaction with 3 different postpartum contraceptive counseling methods.

Study Design: Randomized, prospective trial in an urban medical center. Patients were randomized to receive physician-patient counseling, written literature or an educational video.