Publications by authors named "Molina L"

Background: Self-efficacy theory proposes that confidence to engage in a health behavior is associated with engaging in that specific behavior. Most research examining self-efficacy has been conducted with white young adult populations. This secondary analysis examined the association of self-efficacy (i.

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Background: Evidence-based health promotion programs are commonly assessed within research environments, yet there is a critical need to understand how to implement interventions across multiple settings, prioritizing populations who are underserved and under-resourced. A possible approach involves leveraging established social networks to enhance health outcomes. Within these networks, influential individuals, known as health promoters (HPs), play a key role in disseminating health information.

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Automated touchscreen systems have become increasingly prevalent in rodent model screening. This technology has significantly enhanced cognitive and behavioral assessments in mice and has bridged the translational gap between basic research using rodent models and human clinical research. Our study introduces a custom-built touchscreen operant conditioning chamber powered by a Raspberry Pi and a commercially available computer tablet, which effectively addresses the significant cost barriers traditionally associated with this technology.

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Although current guidelines recommend standard cardiopulmonary exercise testing (CPET) to evaluate symptomatic patients after pulmonary embolism (PE), CPET with simultaneous echocardiography could provide relevant information to evaluate right ventricular-pulmonary arterial coupling. The aim of this study was to investigate exercise-induced changes in echocardiographic variables of RV function or RV- arterial coupling in patients with residual thrombotic defects at 3 months after PE. This retrospective study investigated patients with residual thromboembolic disease on V/Q scintigraphy with persistent symptoms despite adequate anticoagulation after 3 months of acute PE, and resting echocardiography with a low probability of PH.

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Bacteriocins, a class of molecules produced by bacteria, exhibit potent antimicrobial properties, including antiviral activities. The urgent need for treatments against SARS-CoV-2 has proposed bacteriocins such as enterocin DD14 (EntDD14) as potential therapeutic agents. However, the mechanism of macromolecular interaction of EntDD14 for the inhibition of SARS-CoV-2 is not yet fully understood, and its efficacy against variants like JN.

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Extracellular vesicles (EVs), crucial mediators in cell-to-cell communication, are implicated in both homeostatic and pathological processes. Their detectability in easily accessible peripheral fluids like saliva positions them as promising candidates for non-invasive biomarker discovery. However, the lack of standardized methods for salivary EVs isolation greatly limits our ability to study them.

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Salivary microRNAs (miRNAs) have been recently revealed as the next generation of non-invasive biomarkers for the diagnostics of diverse diseases. However, their short and highly homologous sequences make their quantification by RT-qPCR technique highly heterogeneous and study dependent, thus limiting their implementation for clinical applications. In this study, we evaluated the use of a widely used commercial RT-qPCR kit for quantification of salivary miRNAs for clinical diagnostics.

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Article Synopsis
  • - This study investigates how everyday discrimination, childhood trauma, and verbal abuse related to weight affect disordered eating behaviors in individuals in Peru, focusing on those seeking weight loss treatment versus those not seeking it.
  • - The research included 420 participants who completed measures assessing their disordered eating, experiences of discrimination, and childhood traumas.
  • - The findings reveal that those seeking weight loss treatment exhibited higher levels of disordered eating and that discrimination and childhood abuse are linked to these eating issues, indicating a need to address these psychosocial factors in treatment settings.
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Classic Hodgkin lymphoma (HL) is a distinct entity among hematological malignancies of B-cell origin. It is characterized by its unique histopathological features and generally favorable prognosis. Over the years, advancements in understanding its pathogenesis, coupled with refined diagnostic and evaluation modalities, as well as therapeutic strategies, have significantly transformed the landscape of HL management.

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Membrane technologies play a pivotal role in various industrial sectors, including food processing. Membranes act as barriers, selectively allowing the passage of one or other types of species. The separation processes that involve them offer advantages such as continuity, energy efficiency, compactness of devices, operational simplicity, and minimal consumption of chemical reagents.

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Most pediatric specialists, including hematologists/oncologists, surgeons, radiologists, and pathologists, are familiar with the diagnosis and management of Wilms tumor (WT). However, it may be challenging to identify the underlying conditions causing cancer predisposition, which can change the management for the patient and potentially their entire family. In this paper, we present 3 cases of clinically suspected WT associated with Beckwith-Wiedemann syndrome (BWS).

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Richter transformation (RT) is an aggressive lymphoma occurring in patients with chronic lymphocytic leukaemia. Here we investigated the anti-CD3/anti-CD19 T-cell-engager blinatumomab after R-CHOP (i.e.

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Article Synopsis
  • * Research indicates that activation patterns in the BLA differ based on the type of stimulus, with aversive stimuli causing stronger activation in specific medial areas of the BLA and stressful stimuli leading to longer activation durations.
  • * The study highlights the need for further research into the molecular and circuit-level specifics of the BLA's activation during stress, with norepinephrine playing a key role in enhancing neuron responses in these situations.
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Background: After settling in the United States (US), immigrants often accumulate obesity and cardiovascular risk factors. As mood is often associated with health behaviors in the US population, mood may be an important mediating factor in immigrant populations.

Methods: The Healthy Immigrant Community (HIC) study, set in southeast Minnesota, enrolled 475 adult participants in a weight loss intervention designed to reduce cardiovascular risk.

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Cyclophosphamide and ifosfamide are major alkylating agents but their therapeutics uses are limiting by the toxicity due to several toxicities. Indeed conventional chemotherapies are generally used with the maximum tolerated dose. In contrast, metronomic schedule aims to get a minimum dose for efficacy with a good safety.

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Background: The rates of obesity among immigrant populations within the USA rise with increasing duration of residency. The aims of this study were to examine weight self-perception and body image discrepancy within a large community sample of Hispanic and Somali predominantly immigrant adults.

Methods: Utilizing a community-based participatory research (CBPR) approach to collect survey data from a sample of adults who self-identified as Hispanic, Latino, or Somali in Southeast Minnesota.

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Activation of O by subnanometer metal clusters is a fundamental step in the reactivity and oxidation processes of single-cluster catalysts. In this work, we examine the adsorption and dissociation of O on RePt ( + = 5) clusters supported on rutile TiO(110) using DFT calculations. The adhesion energies of RePt clusters on the support are high, indicating significant stability of the supported clusters.

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Smart algorithms for gait kinematic motion prediction in wearable assistive devices including prostheses, bionics, and exoskeletons can ensure safer and more effective device functionality. Although embedded systems can support the use of smart algorithms, there are important limitations associated with computational load. This poses a tangible barrier for models with increased complexity that demand substantial computational resources for superior performance.

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Background: Immigrants to the United States, on average, accumulate cardiovascular risk after resettlement, including obesity. There is a need to co-create interventions to address these disparities, and mood may be an important mediating factor.

Methods: The (HIC) study, set in southeast Minnesota, enrolled 475 adult participants in a weight loss intervention to reduce cardiovascular risk.

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Article Synopsis
  • A 33-year-old man had headaches and vision problems, and doctors found a mass in his brain that was linked to HCL.
  • After treatment with special medicines, he got better quickly and is doing well a year later; other similar cases show that the same treatments can work for more patients with HCL in the brain.
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  • The study estimates pneumonia incidence in elderly patients in Spanish emergency departments, finding an annual rate of 18.4 cases per 1000 inhabitants.
  • A significant 78% of these patients required hospitalization, with 30-day mortality at 14.2% and in-hospital mortality at 12.9%.
  • Factors like functional dependency and severe comorbidity were closely linked to adverse events, while common biomarkers showed only moderate predictive ability for outcomes.
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Monitoring is essential to ensure that environmental goals are being achieved, including those of sustainable agriculture. Growing interest in environmental monitoring provides an opportunity to improve monitoring practices. Approaches that directly monitor land cover change and biodiversity annually by coupling the wall-to-wall coverage from remote sensing and the site-specific community composition from environmental DNA (eDNA) can provide timely, relevant results for parties interested in the success of sustainable agricultural practices.

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  • Chronic thromboembolic pulmonary disease (CTEPD) includes ongoing pulmonary vascular blockages that can limit function, and this study aimed to assess how often these defects and chronic thromboembolic pulmonary hypertension (CTEPH) occur in COVID-19 patients after a pulmonary embolism (PE) within a two-year span.
  • A total of 133 hospitalized COVID-19 patients with PE were observed over two years, with assessments for residual thrombotic defects and their overall health, revealing that 18% had ongoing thrombotic issues and CTEPD incidence was low at 0.75%.
  • Key risk factors for persistent defects included older age, higher incidence of hypertension, elevated D-dimer and NT-proBN
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Article Synopsis
  • Immigrants in the U.S. often struggle with heart health and obesity due to various challenges after moving here.
  • Researchers created a program called the Healthy Immigrant Community to help Hispanic and Somali immigrants in Minnesota improve their health through community support and education.
  • The project will test how well this program works by measuring health improvements over two years, using data like weight, blood pressure, and diet.
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