The periodic anti-seasonal inundation of the Three Gorges Reservoir (TGR) leads to changes in the molecular composition of dissolved organic matter (DOM) in riparian soils, further impacting the geochemical processes and ecological risk of heavy metals. However, the intrinsic driving mechanisms of DOM influencing the cadmium (Cd), a major pollutant in riparian soils in TGR, at the molecular level remain unclear. In this study, the DOM molecular composition, labile Cd in riparian soils and the key driving mechanism before and after flooding were explored using Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), the diffusive gradients in thin films (DGT) and partial least squares path modeling (PLS-PM).
View Article and Find Full Text PDFObjectives: This study aimed to investigate the impact of bioactive plant extracts on the proliferation and migration of dental pulp stem cells (DPSCs) and their potential implications for dental care, focusing on the nurse-caring aspect.
Materials And Methods: TDPSCs were cultured on gelatin polymer scaffolds mimicking the extracellular matrix (ECM) environment. Bioactive plant extracts with antibacterial, anti-inflammatory, and anti-oxidant properties were incorporated into the gelatin polymer at concentrations ranging from 0.
Recently, miRNAs have become a promising biomarker for disease diagnostics. miRNA-145 is closely related to strokes. The accuracy determination of miRNA-145 (miR-145) in stroke patients still remains challenging due to its heterogeneity and low abundance, as well as the complexity of the blood matrix.
View Article and Find Full Text PDFHeavy metals (HMs) in drinking water have drawn worldwide attention due to their risks to public health; however, a systematic assessment of the occurrence of HMs in drinking water treatment plants (DWTPs) at a large geographical scale across China and the removal efficiency, human health risks, and the correlation with environmental factors have yet to be established. Therefore, this study characterised the occurrence patterns of nine conventional dissolved HMs in the influent and effluent water samples from 146 typical DWTPs in seven major river basins across China (which consist of the Yangtze River, the Yellow River, the Songhua River, the Pearl River, the Huaihe River, the Liaohe River and the Haihe River) for the first time and removal efficiency, probabilistic health risks, and the correlation with water quality. According to the findings, a total of eight HMs (beryllium (Be), antimony (Sb), barium (Ba), molybdenum (Mo), nickel (Ni), vanadium (V), cobalt (Co) and titanium (Ti)) were detected, with detection frequencies in influent and effluent water ranging from 2.
View Article and Find Full Text PDFThe Modaomen and Hongwan waterways are the main estuaries of the Pearl River system. Affected by tides, the Fenghuangshan Reservoir, Dajingshan Reservoir, and Zhuxiandong Reservoir, which are subject to water transfer along the river line, are important drinking water sources in the central part of Zhuhai City in the Guangdong-Hong Kong-Macao Greater Bay Area. Eight heavy metals in 15 sampling points in the reservoir area were monitored in the two seasons (August and October) of 2019.
View Article and Find Full Text PDFExosomal MicroRNA-21 (miRNA-21, miR-21) is significantly up-regulated in blood samples of patients with lung cancer. Exosomal-derived miR-21 can be used as a promising biomarker for the early diagnosis of lung cancer. This paper develops a fluorescent biosensor based on the combination of magnetic nanoparticles (MNPs), cascade strand displacement reaction (CSDR) and CRISPR/Cas12a to detect the exosomal miR-21 from lung cancer.
View Article and Find Full Text PDFThe Douhe Reservoir is an important diversion water source and drinking water resource for Tianjin and the Tangshan cities. Panjiakou, Daheiting, Qiuzhuang, and the Douhe Reservoirs located from top to bottom in the LuanHe River region forming a group of cascade reservoirs. After over 30 years of aquaculture, the concentration of nitrogen (N) and phosphorus (P) have exceeded Class III of Environmental Quality Standard for Surface Water in China.
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