Publications by authors named "Moldovan Sabov"
Article Synopsis
- Simple kidney cysts are common and typically seen as unimportant but may be linked to worsened chronic kidney disease (CKD) outcomes, especially in older patients with lower kidney function.
- * An observational study examined patients who underwent radical nephrectomy, analyzing the size and location of kidney cysts to see how they correlate with kidney health over time.
- * Results showed that having more kidney cysts, particularly medullary ones, increased the risk of progressive CKD events, indicating a potential need for reevaluating the clinical relevance of these cysts in kidney disease.
Background: Semiquantitative visual inspection for glomerulosclerosis, interstitial fibrosis, and arteriosclerosis is often used to assess chronic changes in native kidney biopsies. Morphometric evaluation of these and other chronic changes may improve the prognostic assessment.
Methods: We studied a historical cohort of patients who underwent a native kidney biopsy between 1993 and 2015 and were followed through 2021 for ESKD and for progressive CKD (defined as experiencing 50% eGFR decline, temporary dialysis, or ESKD).
Objective: Pulmonary hypertension (PH) is a substantial preoperative risk factor. For this study, morbidity and mortality were examined after noncardiac surgery in patients with precapillary PH.
Design: A retrospective cohort study.
Improving Diagnostic Fidelity: An Approach to Standardizing the Process in Patients With Emerging Critical Illness.
Mayo Clin Proc Innov Qual Outcomes
September 2019
Objective: To reliably improve diagnostic fidelity and identify delays using a standardized approach applied to the electronic medical records of patients with emerging critical illness.
Patients And Methods: This retrospective observational study at Mayo Clinic, Rochester, Minnesota, conducted June 1, 2016, to June 30, 2017, used a standard operating procedure applied to electronic medical records to identify variations in diagnostic fidelity and/or delay in adult patients with a rapid response team evaluation, at risk for critical illness. Multivariate logistic regression analysis identified predictors and compared outcomes for those with and without varying diagnostic fidelity and/or delay.
Objective: To investigate whether older adults with mild cognitive impairment (MCI) or dementia have higher rates of procedures requiring general anesthesia or intensive care unit (ICU) admissions compared with cognitively normal (CN) patients.
Patients And Methods: A population-based cohort, 70 to 89 years old at enrollment, underwent clinical and longitudinal neurocognitive testing to identify those with MCI and dementia. We analyzed the effects of cognitive status (CN, MCI, or dementia) at entry into the study from October 1, 2004, through December 31, 2014, on the risk of receiving procedures requiring surgical anesthesia and ICU admission.
Objectives: To evaluate the epidemiology of hyperammonemia unrelated to liver failure in the critical care setting.
Design: Retrospective case series.
Setting: Critically ill patients admitted to ICUs at Mayo Clinic, Rochester, MN (medical ICU, two mixed medical-surgical ICUs, coronary care unit, or the cardiosurgical ICU) between July 1, 2004, and October 31, 2015.