During the postictal period, the left cerebral hemisphere was affected by the seizures, and consecutive epileptiform discharges and disinhibition of the right cerebral hemisphere could have occurred, which may explain the observed behavior.
View Article and Find Full Text PDFAntibiot Khimioter
January 2010
From the clinicoeconomic viewpoints the treatment of community-acquired pneumonia in patients without risk factors under hospital conditions with aminopenicillins was more appropriate, whereas for the treatment of patients with risk factors the following scheme of antibiotic therapy was advantageous: a beta-lactam (cefotaxime/ceftriaxone) in combination with a macrolide (azithromycin). The recommended therapy provided statistically lower percentage of negative pneumonia processes and decreased the treatment expenditures.
View Article and Find Full Text PDFThe rate of acetylation of xenobiotics affects the course and prognosis of infectious diseases. The efficacy of antibiotic therapy of community-acquired pneumonia in RA-patients is lower than that in LA-ones. In order to ensure the best antimicrobial effect on the onset of the disease it is required to use regimens with the maximum permissible dose of antibacterial drugs in the regions where the rapid type prevails.
View Article and Find Full Text PDFCombined antibiotic therapy, including the use of intravenous cefotaxime (a beta-lactam) and azithromycin (a macrolide) was shown advantageous from both clinical and economic viewpoints in the treatment of severe community-acquired pneumonia.
View Article and Find Full Text PDFProbl Tuberk Bolezn Legk
January 2008
The purpose of the present investigation was to study the composition of patients with caseous pneumonia (CP), its causes, and fetal outcomes in relation to sex. A hundred and ninety-eight patients, including 139 males and 59 females, were examined. There was a high proportion of socially dysadapted persons particularly among males.
View Article and Find Full Text PDFThe method of cancer risk assessment on the basis of the Fuzzy Set Theory is presented. The method is based on a multifactor risk assessment of cancer diseases. The individual risk of cancer disease is evaluated as the probability of disease multiplied by the value of an individual dose.
View Article and Find Full Text PDFSelf-concept in old age was investigated. The goal of the work was to reveal the contents of self-concept, that is, what is included in the sphere of self-assessment, and also to analyze the traditional parameters of self-assessment: its height, stability, adequacy. Specific features of self-concept in old age were found.
View Article and Find Full Text PDFThe drug gevilon that produces hypolipidemic effects has been clinically tested. The drug was used to treat 53 patients suffering from coronary heart disease, hypertensive disease with severe lipid metabolic disturbances. Gevilon has been found to have a hypolipidemic effect in reducing the levels of total cholesterol, beta-cholesterol, triglycerides, increasing alpha-cholesterol levels and normalizing the atherogenicity coefficient.
View Article and Find Full Text PDFThe effects of some natural polypeptides fragments and amino acids which were incorporated in them on the thymus-dependent SRBC immune response and on the phagocytosis of Staphylococcus by murine peritoneal neutrophils were compared. It was found that the peptides LGIP and PYIK which consisted of those amino acids that stimulated phagocytosis but did influence the immune response (K, P, Y, L) did not change the immune response as well as phagocytosis. The peptides TKPR, TTKD and LGIPE which included those amino acids that were able to stimulate both immune response and phagocytosis (T, E, D) enhanced both activities.
View Article and Find Full Text PDFThe paper deals with methodological problems of electrolyte intake in clinical and population-based studies. Marked inter- and intraindividual fluctuations were found to substantially affect the reliability of assessing the intake of electrolytes, which should be borne in mind in practice. Specifically, individual-based reliable characteristics of electrolyte intake (excretion) may be obtained after examining at least 8 daily urinary collections.
View Article and Find Full Text PDFPlatelet and plasma lipid peroxidation (LPO) activity, and possible effect of LPO products on platelet membrane structure were examined in patients with unstable angina, an acute form of coronary disease. All parameters of LPO were increased both in the platelets and the plasma. It was demonstrated by spinning probes that platelet membrane S degree of order was increased significantly, an evidence of increased microviscosity, in patients with unstable angina.
View Article and Find Full Text PDFProbl Endokrinol (Mosk)
June 1989