Publications by authors named "Mokhtar Boutahala"

Article Synopsis
  • The study focused on creating microspheres containing Mesalazine (5-ASA) for targeted drug delivery to the colon, using an emulsion solvent evaporation method.
  • The formulation included sodium alginate and ethylcellulose as encapsulating agents and polyvinyl alcohol as an emulsifier while examining the impact of various processing parameters on the microspheres' properties.
  • Characterization methods included optical microscopy and spectroscopy, and drug release was tested in simulated gastric and intestinal fluids, with kinetic results analyzed under specific mathematical models to evaluate drug liberation.
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Chitosan/bentonite beads (CsB) composites were prepared from chitosan (Cs) and bentonite (B) and cross-linked with epichlorohydrin for removal of reactive orange 16 (RO16) and methylene blue (MB). The adsorption results have shown that the (Cs20B80), 20 % wt of (Cs) and 80 % (B), was selected as the best adsorbent for (MB) and (RO16) dyes. SEM, EDX, FTIR, BET, and pHpzc were implemented to investigate the features of Cs, B, and Cs20B80 samples.

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The aim of this study was to prepare and characterise inclusion complexes of a low water-soluble drug, mefenamic acid (MA), with β-cyclodextrin (β-CD). First, the phase solubility diagram of MA in β-CD was drawn from 0 to 21 × 10 M of β-CD concentration. A job's plot experiment was used to determine the stoichiometry of the MA:β-CD complex (2:1).

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Magnetic beads (AO-γ-FeO) of alginate (A) impregnated with citrate coated maghemite nanoparticles (γ-FeO) and oxidized multiwalled carbon nanotubes (OMWCNTs) were synthesized and used as adsorbent for the removal of methylene blue from water. The XRD analysis revealed that the diameter of γ-FeO is 10.24 nm.

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The present work focused on the performance of chitosan/polyaniline (Cht-PANI) composite for removing tartrazine dye from aqueous solutions. The adsorbent was characterized using SEM, XRD, FTIR, and TGA/DTA techniques. The effects of pH, initial dye concentration, contact time, and temperature on azo dye removal were studied.

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Article Synopsis
  • The study investigated the effectiveness of three materials—acid-activated organobentonite (OAB), calcium alginate (A), and a composite bead (A-OAB)—in removing methylene blue dye from water.
  • The researchers evaluated various factors like pH, temperature, and initial dye concentration, finding that the maximum adsorption capacities at 25°C were 263.80 mg/g for OAB, 483.6 mg/g for A, and 799.43 mg/g for A-OAB.
  • Results showed that the adsorption could be described by the pseudo-second-order kinetic model and suggested that A-OAB is a cost-effective option for removing dyes from wastewater, with a slight decrease in efficiency after multiple uses.
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